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Rhesus macaque LILRB1/CD85j/ILT2 Protein 3248

$300.00$1,000.00

Summary

  • Expression: HEK293
  • Binding assay: Yes (SPR)
  • Amino Acid Range: Met1-His474
SKU: 3248parent Categories: , Tag:
Weight1 lbs
Dimensions9 × 5 × 2 in
accession

NP_001035762.2

express system

HEK293

product tag

C-His

purity

> 95% as determined by Tris-Bis PAGE;> 95% as determined by HPLC

background

LILRB1, also known as CD85j and ILT2, is a 110 kDa transmembrane glycoprotein in the LILR immunoregulatory protein family. Mature human LILRB1 consists of a 438 amino acid (aa) extracellular domain (ECD) with 4 tandem Ig-like domains, a 21 aa transmembrane segment, and a 168 aa cytoplasmic domain with 4 inhibitory ITIM motifs.LILRB1 is a receptor for class I MHC antigens. Recognizes a broad spectrum of HLA-A, HLA-B, HLA-C, HLA-G and HLA-F alleles. Receptor for H301/UL18, a human cytomegalovirus class I MHC homolog. Ligand binding results in inhibitory signals and down-regulation of the immune response.

molecular weight

The protein has a predicted MW of 48.08 kDa. Due to glycosylation, the protein migrates to 65-70 kDa based on Tris-Bis PAGE result.

available size

100 µg, 500 µg

endotoxin

Less than 1EU per μg by the LAL method.

Rhesus macaque LILRB1/CD85j/ILT2 Protein 3248

protein
Size and concentration
100, 500µg and lyophilized
Form
Lyophilized
Storage Instructions
Valid for 12 months from date of receipt when stored at -80°C. Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
Storage buffer
Shipped at ambient temperature.
Purity
> 95% as determined by Tris-Bis PAGE
No information
target relevance

SPR with Rhesus macaque LILRB1/CD85j/ILT2 Protein
Anti-LILRB1 Antibody captured on CM5 Chip via Protein A can bind Rhesus macaque LILRB1, His Tag with an affinity constant of 36.75 nM as determined in SPR assay (Biacore T200).
HPLC of Rhesus macaque LILRB1/CD85j/ILT2 Protein
The purity of Rhesus macaque LILRB1 is greater than 95% as determined by SEC-HPLC.
SDS-PAGE gel of Rhesus macaque LILRB1/CD85j/ILT2 Protein
Rhesus macaque LILRB1 on Tris-Bis PAGE under reduced condition. The purity is greater than 95%.

Publications

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We haven't added any publications to our database yet.
Published literature highly relevant to the biological target of this product and referencing this antibody or clone are retrieved from PubMed database provided by The United States National Library of Medicine at the National Institutes of Health.

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