Cynomolgus HLA-G&B2M&Peptide (RIIPRHLQL) Monomer Protein 3160

$310.00 – $1,125.00

Summary

Expression: HEK293
Pure: Yes (HPLC)
Amino Acid Range: Gly25-Thr305(HLA-G),Ile21-Met119(B2M)and RIIPRHLQL peptide

available size

Clear

SKU: 3160parent Categories: proteins, Recombinant proteins Tag: active proteins

Weight	1 lbs
Dimensions	9 × 5 × 2 in
accession	E0WKX9(HLA-G)&Q8SPW0(B2M)&RIIPRHLQL
express system	HEK293
product tag	C-His-Avi
purity	> 95% as determined by Tris-Bis PAGE;> 95% as determined by HPLC
background	HLA-G is a molecule that was first known to confer protection to the fetus from destruction by the immune system of its mother, thus critically contributing to fetal-maternal tolerance. The first functional finding constituted the basis for HLA-G research and can be summarized as such: HLA-G, membrane-bound or soluble, strongly binds its inhibitory receptors on immune cells (NK, T, B, monocytes/dendritic cells), inhibits the functions of these effectors, and so induces immune inhibition.
molecular weight	The protein has a predicted MW of 50.6 kDa. Due to glycosylation, the protein migrates to 55-65 kDa based on Tris-Bis PAGE result.
available size	100 µg, 500 µg
endotoxin	Less than 1EU per μg by the LAL method.

Cynomolgus HLA-G&B2M&Peptide (RIIPRHLQL) Monomer Protein 3160

protein

Size and concentration 100, 500µg and lyophilized
Form Lyophilized
Storage Instructions Valid for 12 months from date of receipt when stored at -80°C. Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
Storage buffer Shipped at ambient temperature.
Purity > 95% as determined by Tris-Bis PAGE

target relevance
HLA-G is a molecule that was first known to confer protection to the fetus from destruction by the immune system of its mother, thus critically contributing to fetal-maternal tolerance. The first functional finding constituted the basis for HLA-G research and can be summarized as such: HLA-G, membrane-bound or soluble, strongly binds its inhibitory receptors on immune cells (NK, T, B, monocytes/dendritic cells), inhibits the functions of these effectors, and so induces immune inhibition.
Protein names MHC class I antigen
Gene names Mafa-AG,Mafa-AG
Protein family MHC class I family
Mass 9541Da
Function Involved in the presentation of foreign antigens to the immune system.
Subellular location Membrane ; Single-pass type I membrane protein .
Target Relevance information above includes information from UniProt accession: E0WKX9
The UniProt Consortium

Data

HPLC of Cynomolgus HLA-G&B2M&Peptide (RIIPRHLQL) Monomer Protein

The purity of Cynomolgus HLA-G&B2M&Peptide (RIIPRHLQL) Monomer is greater than 95% as determined by SEC-HPLC.

SDS-PAGE gel of Cynomolgus HLA-G&B2M&Peptide (RIIPRHLQL) Monomer Protei

Cynomolgus HLA-G&B2M&Peptide (RIIPRHLQL) Monomer on Tris-Bis PAGE under reduced condition. The purity is greater than 95%.

Publications

pmid	title	authors	citation
We haven't added any publications to our database yet.

Published literature highly relevant to the biological target of this product and referencing this antibody or clone are retrieved from PubMed database provided by The United States National Library of Medicine at the National Institutes of Health.