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Human CTGF/CCN2 Protein 3154

$315.00$1,050.00

Summary

  • Expression: HEK293
  • Functional: Yes (ELISA)
  • Amino Acid Range: Gln27-Ala349
SKU: 3154parent Categories: , Tag:
Weight 1 lbs
Dimensions 9 × 5 × 2 in
accession

Q5M8T4

express system

HEK293

product tag

N-hFc

purity

> 95% as determined by Tris-Bis PAGE;> 95% as determined by HPLC

background

Connective tissue growth factor (CTGF) is a member of the CCN matricellular protein family, consisting of four domains, that regulates the signaling of other growth factors and promotes kidney fibrosis.CTGF can simultaneously interact with several factors with its four domains. The microenvironment differs depending on the types of cells and tissues and differentiation stages of these cells.

molecular weight

The protein has a predicted MW of 61.77 kDa. Due to glycosylation, the protein migrates to 50-55 kDa and 62-72 kDa based on Tris-Bis PAGE result.

available size

100 µg, 500 µg

endotoxin

Less than 1EU per μg by the LAL method.

Human CTGF/CCN2 Protein 3154

protein
Size and concentration
100, 500µg and lyophilized
Form
Lyophilized
Storage Instructions
Valid for 12 months from date of receipt when stored at -80°C. Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
Storage buffer
Shipped at ambient temperature.
Purity
> 95% as determined by Tris-Bis PAGE
target relevance
Connective tissue growth factor (CTGF) is a member of the CCN matricellular protein family, consisting of four domains, that regulates the signaling of other growth factors and promotes kidney fibrosis.CTGF can simultaneously interact with several factors with its four domains. The microenvironment differs depending on the types of cells and tissues and differentiation stages of these cells.
Protein names
CCN family member 2 (Cellular communication network factor 2) (Connective tissue growth factor)
Gene names
CTGF,CTGF
Protein family
CCN family
Mass
9606Da
Subellular location
Secreted, extracellular space, extracellular matrix .
Target Relevance information above includes information from UniProt accession: Q5M8T4
The UniProt Consortium

Data

ELISA with Human CTGF/CCN2 Protein
Immobilized Human CTGF, hFc Tag at 0.2µg/ml (100µl/Well) on the plate. Dose response curve for Biotinylated Anti-CTGF Antibody, hFc Tag with the EC50 of 14.2ng/ml determined by ELISA.
HPLC of Human CTGF/CCN2 Protein
The purity of Human CTGF is greater than 95% as determined by SEC-HPLC.
SDS-PAGE gel of Human CTGF/CCN2 Protein
Human CTGF on Tris-Bis PAGE under reduced condition. The purity is greater than 95%.

Publications

Publications

pmid title authors citation
We haven't added any publications to our database yet.
Published literature highly relevant to the biological target of this product and referencing this antibody or clone are retrieved from PubMed database provided by The United States National Library of Medicine at the National Institutes of Health.

Protocols

relevant to this product

Documents

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