Biotinylated Human BTN3A2 Protein 3129

$525.00 – $1,750.00

Summary

Expression: HEK293
Pure: Yes (HPLC)
Amino Acid Range: Gln30-Trp248

SKU: 3129parent Categories: proteins, Recombinant proteins Tag: active proteins

Weight	1 lbs
Dimensions	9 × 5 × 2 in
express system	HEK293
product tag	C-His-Avi
purity	> 95% as determined by Tris-Bis PAGE;> 93% as determined by HPLC
background	BTN3A2/BT3.2 butyrophilin mRNA expression by tumoral cells was previously identified as a prognostic factor in a small cohort of high grade serous epithelial ovarian cancer (HG-EOC).In conclusion, BT3.2 protein is a potential prognostic biomarker for the identification of HG-EOC patients with better outcome. In contrast, high CD206 /CD68 expression is associated with high risk of disease progression.
molecular weight	The protein has a predicted MW of 26.5 kDa. Due to glycosylation, the protein migrates to 30-38 kDa based on Tris-Bis PAGE result.
available size	100 µg, 500 µg
endotoxin	Less than 1EU per μg by the LAL method.

Biotinylated Human BTN3A2 Protein 3129
protein
Size and concentration
100, 500µg and lyophilized
Form
Lyophilized
Storage Instructions
Valid for 12 months from date of receipt when stored at -80°C. Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
Storage buffer
Shipped at ambient temperature.
Purity
> 95% as determined by Tris-Bis PAGE
target relevance
BTN3A2/BT3.2 butyrophilin mRNA expression by tumoral cells was previously identified as a prognostic factor in a small cohort of high grade serous epithelial ovarian cancer (HG-EOC).In conclusion, BT3.2 protein is a potential prognostic biomarker for the identification of HG-EOC patients with better outcome. In contrast, high CD206 /CD68 expression is associated with high risk of disease progression.
Protein names
Butyrophilin subfamily 3 member A2
Gene names
BTN3A2,BTN3A2 BT3.2 BTF3 BTF4
Protein family
Immunoglobulin superfamily, BTN/MOG family
Mass
9606Da
Function
Plays a role in T-cell responses in the adaptive immune response. Inhibits the release of IFNG from activated T-cells.
Subellular location
Cell membrane ; Single-pass type I membrane protein .
Tissues
Detected in T-cells and natural killer cells.
Structure
Homodimer.
Post-translational modification
N-glycosylated.
Target Relevance information above includes information from UniProt accession: P78410
The UniProt Consortium

HPLC of Biotinylated Human BTN3A2 Protein

The purity of Biotinylated Human BTN3A2 is greater than 93% as determined by SEC-HPLC.

SDS-PAGE gel of Biotinylated Human BTN3A2 Protein

Biotinylated Human BTN3A2 on Tris-Bis PAGE under reduced condition. The purity is greater than 95%.

Publications

pmid	title	authors	citation
We haven't added any publications to our database yet.

Published literature highly relevant to the biological target of this product and referencing this antibody or clone are retrieved from PubMed database provided by The United States National Library of Medicine at the National Institutes of Health.