Weight | 1 lbs |
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Dimensions | 9 × 5 × 2 in |
express system | E.coli |
product tag | N-His |
purity | > 95% as determined by Tris-Bis PAGE |
background | Peptidylarginine deiminase type4 (PADI4) was firstly identified as a non-MHC RA genetic risk factor. Furthermore, PADI4 risk allele possessed the association with bone damage regardless of anti citrullinated peptide antibody (ACPA) positivity in Asian RA patients. PADI4 gene codes PAD4 protein which has post-translational modification activity (citrullination). Padi4 is mainly expressed in myeloid cells and granulocytes. |
molecular weight | The protein has a predicted MW of 76.6 kDa same as Tris-Bis PAGE result. |
available size | 100 µg, 500 µg |
endotoxin | Less than 1EU per μg by the LAL method. |
Biotinylated Cynomolgus PADI4 Protein (Primary Amine Labeling) 3087
$675.00 – $2,250.00
Summary
- Expression: E.coli
- Pure: Yes (SDS-PAGE)
- Amino Acid Range: Met1-Pro663
Biotinylated Cynomolgus PADI4 Protein (Primary Amine Labeling) 3087
protein |
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Size and concentration 100, 500µg and liquid |
Form Liquid |
Storage Instructions Valid for 12 months from date of receipt when stored at -80°C. Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles. |
Storage buffer Shipped with dry ice. |
Purity > 95% as determined by Tris-Bis PAGE |
target relevance |
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Peptidylarginine deiminase type4 (PADI4) was firstly identified as a non-MHC RA genetic risk factor. Furthermore, PADI4 risk allele possessed the association with bone damage regardless of anti citrullinated peptide antibody (ACPA) positivity in Asian RA patients. PADI4 gene codes PAD4 protein which has post-translational modification activity (citrullination). Padi4 is mainly expressed in myeloid cells and granulocytes. |
Protein names Protein-arginine deiminase (EC 3.5.3.15) |
Gene names PADI4,PADI4 |
Protein family Protein arginine deiminase family |
Mass 9541Da |
Function Catalyzes the deimination of arginine residues of proteins. |
Subellular location Cytoplasm . |
Target Relevance information above includes information from UniProt accession: A0A2K5USI5 |
The UniProt Consortium |
Biotinylated Cynomolgus PADI4 (Primary Amine Labeling) on Tris-Bis PAGE under reduced condition. The purity is greater than 95%. |
Publications
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