Rhesus macaque VEGF R2/KDR Protein 3038

$240.00 – $800.00

Summary

Expression: HEK293
Functional: Yes (ELISA)
Amino Acid Range: Ala20-Glu764

available size

Clear

SKU: 3038parent Categories: proteins, Recombinant proteins Tag: active proteins

Weight	1 lbs
Dimensions	9 × 5 × 2 in
accession	F7E313
express system	HEK293
product tag	C-His
purity	> 95% as determined by Tris-Bis PAGE;> 95% as determined by HPLC
background	Tyrosine-protein kinase that acts as a cell-surface receptor for VEGFA, VEGFB and PGF, and plays an essential role in the development of embryonic vasculature, the regulation of angiogenesis, cell survival, cell migration, macrophage function, chemotaxis, and cancer cell invasion. The tyrosine kinase receptor vascular endothelial growth factor receptor 2 (VEGFR2) is a key regulator of angiogenesis.
molecular weight	The protein has a predicted MW of 84.37 kDa. Due to glycosylation, the protein migrates to 115-145 kDa based on Tris-Bis PAGE result.
available size	100 µg, 500 µg
endotoxin	Less than 1EU per μg by the LAL method.

Rhesus macaque VEGF R2/KDR Protein 3038

protein

Size and concentration 100, 500µg and lyophilized
Form Lyophilized
Storage Instructions Valid for 12 months from date of receipt when stored at -80°C. Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
Storage buffer Shipped at ambient temperature.
Purity > 95% as determined by Tris-Bis PAGE

target relevance
Tyrosine-protein kinase that acts as a cell-surface receptor for VEGFA, VEGFB and PGF, and plays an essential role in the development of embryonic vasculature, the regulation of angiogenesis, cell survival, cell migration, macrophage function, chemotaxis, and cancer cell invasion. The tyrosine kinase receptor vascular endothelial growth factor receptor 2 (VEGFR2) is a key regulator of angiogenesis.
Protein names Vascular endothelial growth factor receptor 2 (EC 2.7.10.1)
Gene names KDR,KDR
Protein family Protein kinase superfamily, Tyr protein kinase family, CSF-1/PDGF receptor subfamil
Mass 9544Da
Catalytic activity BINDING 868; /ligand="ATP"; /ligand_id="ChEBI:CHEBI:30616"; /evidence="ECO:0000256\|PROSITE-ProRule:PRU10141"; BINDING 1033; /ligand="Mg(2+)"; /ligand_id="ChEBI:CHEBI:18420"; /evidence="ECO:0000256\|PIRSR:PIRSR000615-3"; BINDING 1046; /ligand="Mg(2+)"; /ligand_id="ChEBI:CHEBI:18420"; /evidence="ECO:0000256\|PIRSR:PIRSR000615-3"
Subellular location Cell membrane ; Single-pass type I membrane protein. Cytoplasmic vesicle. Early endosome. Endoplasmic reticulum. Endosome. Membrane ; Single-pass type I membrane protein. Vesicle .
Target Relevance information above includes information from UniProt accession: F7E313
The UniProt Consortium

Data

ELISA with Rhesus macaque VEGF R2/KDR Protein

Immobilized Rhesus macaque VEGF R2, His Tag at 0.2µg/ml (100µl/Well) on the plate. Dose response curve for Anti-VEGF R2 Antibody, hFc Tag with the EC50 of 19.6ng/ml determined by ELISA.

HPLC of Rhesus macaque VEGF R2/KDR Protein

The purity of Rhesus macaque VEGF R2 is greater than 95% as determined by SEC-HPLC.

SDS-PAGE gel of Rhesus macaque VEGF R2/KDR Protein

Rhesus macaque VEGF R2 on Tris-Bis PAGE under reduced condition. The purity is greater than 95%.

Publications

pmid	title	authors	citation
We haven't added any publications to our database yet.

Published literature highly relevant to the biological target of this product and referencing this antibody or clone are retrieved from PubMed database provided by The United States National Library of Medicine at the National Institutes of Health.