Weight | 1 lbs |
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Dimensions | 9 × 5 × 2 in |
accession | Q8V4U9 |
express system | HEK293 |
product tag | N-His |
purity | > 95% as determined by Tris-Bis PAGE;> 95% as determined by HPLC |
background | Monkeypox virus (MPXV) is double-stranded DNA virus belonging to the genus orthopoxvirus that causes a smallpox-like disease in humans. A30L is an envelope protein required for the fusion of virus and host cell to form syncytia, and is also considered to be an important target in MPXV research. |
molecular weight | The protein has a predicted MW of 15.24 kDa. Due to glycosylation, the protein migrates to 30-55 kDa based on Tris-Bis PAGE result. |
available size | 100 µg, 500 µg |
endotoxin | Less than 1EU per μg by the LAL method. |
Monkeypox virus A30 Protein 2925
$270.00 – $900.00
Summary
- Expression: HEK293
- Pure: Yes (HPLC)
- Amino Acid Range: Gln22-Leu146
Monkeypox virus A30 Protein 2925
protein |
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Size and concentration 100, 500µg and lyophilized |
Form Lyophilized |
Storage Instructions Valid for 12 months from date of receipt when stored at -80°C. Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles. |
Storage buffer Shipped at ambient temperature. |
Purity > 95% as determined by Tris-Bis PAGE |
target relevance |
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Monkeypox virus (MPXV) is double-stranded DNA virus belonging to the genus orthopoxvirus that causes a smallpox-like disease in humans. A30L is an envelope protein required for the fusion of virus and host cell to form syncytia, and is also considered to be an important target in MPXV research. |
Protein names Envelope protein OPG155 (Protein A30) |
Gene names OPG155,OPG155 A30L |
Protein family Orthopoxvirus OPG155 protein family |
Mass 619591Da |
Function Envelope protein required for virus entry into host cell and for cell-cell fusion (syncytium formation). |
Subellular location Virion membrane ; Single-pass type III membrane protein. Note=Component of the mature virion (MV) membrane. |
Structure Part of a stable entry-fusion complex (EFC) which is at least composed of proteins OPG143, OPG147, OPG155, OPG086, OPG094, OPG107, OPG104, and OPG099. Formation of the viral membrane is necessary for the assembly of the complex. Interacts directly with protein OPG107. |
Post-translational modification Contains two intramolecular disulfide bonds. They are created by the viral disulfide bond formation pathway, a poxvirus-specific pathway that operates on the cytoplasmic side of the MV membranes. |
Target Relevance information above includes information from UniProt accession: Q8V4U9 |
The UniProt Consortium |
Data
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The purity of Monkeypox virus A30 is greater than 95% as determined by SEC-HPLC. |
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Monkeypox virus A30 on Tris-Bis PAGE under reduced condition. The purity is greater than 95%. |
Publications
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