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Monkeypox virus A30 Protein 2925

$270.00$900.00

Summary

  • Expression: HEK293
  • Pure: Yes (HPLC)
  • Amino Acid Range: Gln22-Leu146
Weight 1 lbs
Dimensions 9 × 5 × 2 in
accession

Q8V4U9

express system

HEK293

product tag

N-His

purity

> 95% as determined by Tris-Bis PAGE;> 95% as determined by HPLC

background

Monkeypox virus (MPXV) is double-stranded DNA virus belonging to the genus orthopoxvirus that causes a smallpox-like disease in humans. A30L is an envelope protein required for the fusion of virus and host cell to form syncytia, and is also considered to be an important target in MPXV research.

molecular weight

The protein has a predicted MW of 15.24 kDa. Due to glycosylation, the protein migrates to 30-55 kDa based on Tris-Bis PAGE result.

available size

100 µg, 500 µg

endotoxin

Less than 1EU per μg by the LAL method.

Monkeypox virus A30 Protein 2925

protein
Size and concentration
100, 500µg and lyophilized
Form
Lyophilized
Storage Instructions
Valid for 12 months from date of receipt when stored at -80°C. Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
Storage buffer
Shipped at ambient temperature.
Purity
> 95% as determined by Tris-Bis PAGE
target relevance
Monkeypox virus (MPXV) is double-stranded DNA virus belonging to the genus orthopoxvirus that causes a smallpox-like disease in humans. A30L is an envelope protein required for the fusion of virus and host cell to form syncytia, and is also considered to be an important target in MPXV research.
Protein names
Envelope protein OPG155 (Protein A30)
Gene names
OPG155,OPG155 A30L
Protein family
Orthopoxvirus OPG155 protein family
Mass
619591Da
Function
Envelope protein required for virus entry into host cell and for cell-cell fusion (syncytium formation).
Subellular location
Virion membrane ; Single-pass type III membrane protein. Note=Component of the mature virion (MV) membrane.
Structure
Part of a stable entry-fusion complex (EFC) which is at least composed of proteins OPG143, OPG147, OPG155, OPG086, OPG094, OPG107, OPG104, and OPG099. Formation of the viral membrane is necessary for the assembly of the complex. Interacts directly with protein OPG107.
Post-translational modification
Contains two intramolecular disulfide bonds. They are created by the viral disulfide bond formation pathway, a poxvirus-specific pathway that operates on the cytoplasmic side of the MV membranes.
Target Relevance information above includes information from UniProt accession: Q8V4U9
The UniProt Consortium

Data

HPLC of Monkeypox virus A30 Protein
The purity of Monkeypox virus A30 is greater than 95% as determined by SEC-HPLC.
SDS-PAGE gel of Monkeypox virus A30 Protein
Monkeypox virus A30 on Tris-Bis PAGE under reduced condition. The purity is greater than 95%.

Publications

Publications

pmid title authors citation
We haven't added any publications to our database yet.
Published literature highly relevant to the biological target of this product and referencing this antibody or clone are retrieved from PubMed database provided by The United States National Library of Medicine at the National Institutes of Health.

Protocols

relevant to this product

Documents

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