ELISA with Cynomolgus CD30/TNFRSF8 Protein 3075

Cynomolgus CD30/TNFRSF8 Protein 3075

$315.00 – $1,050.00

Summary

Expression: HEK293
Functional: Yes (ELISA)
Amino Acid Range: Ala27-Pro394

SKU: 3075parent Categories: proteins, Recombinant proteins Tag: active proteins

Weight	1 lbs
Dimensions	9 × 5 × 2 in
accession	A0A2K5VW07
express system	HEK293
product tag	C-His
purity	> 95% as determined by Tris-Bis PAGE;> 95% as determined by HPLC
background	The transmembrane receptor CD30 (TNFRSF8) and its ligand CD30L (CD153, TNFSF8) are members of the tumor necrosis factor (TNF) superfamily and display restricted expression in subpopulations of activated T-and B-cells in nonpathologic conditions. CD30 expression is upregulated in various hematological malignancies, including Reed-Sternberg cells in Hodgkin's disease (HD), anaplastic large cell lymphoma (ALCL) and subsets of Non-Hodgkin's lymphomas (NHLs).
molecular weight	The protein has a predicted MW of 39.86 kDa. Due to glycosylation, the protein migrates to 75-105 kDa based on Tris-Bis PAGE result.
available size	100 µg, 500 µg
endotoxin	Less than 1EU per μg by the LAL method.

Cynomolgus CD30/TNFRSF8 Protein 3075

protein

Size and concentration 100, 500µg and lyophilized
Form Lyophilized
Storage Instructions Valid for 12 months from date of receipt when stored at -80°C. Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
Storage buffer Shipped at ambient temperature.
Purity > 95% as determined by Tris-Bis PAGE

target relevance
The transmembrane receptor CD30 (TNFRSF8) and its ligand CD30L (CD153, TNFSF8) are members of the tumor necrosis factor (TNF) superfamily and display restricted expression in subpopulations of activated T-and B-cells in nonpathologic conditions. CD30 expression is upregulated in various hematological malignancies, including Reed-Sternberg cells in Hodgkin's disease (HD), anaplastic large cell lymphoma (ALCL) and subsets of Non-Hodgkin's lymphomas (NHLs).
Protein names TNF receptor superfamily member 8
Gene names TNFRSF8,TNFRSF8
Mass 9541Da
Target Relevance information above includes information from UniProt accession: A0A2K5VW07
The UniProt Consortium

Data

ELISA with Cynomolgus CD30/TNFRSF8 Protein

Immobilized Cynomolgus CD30, His Tag at 0.5µg/ml (100µl/Well) on the plate. Dose response curve for Anti-CD30 Antibody, hFc Tag with the EC50 of 10.5ng/ml determined by ELISA.

The purity of Cynomolgus CD30 is greater than 95% as determined by SEC-HPLC.

SDS-PAGE gel of Cynomolgus CD30/TNFRSF8 Protein

Cynomolgus CD30 on Tris-Bis PAGE under reduced condition. The purity is greater than 95%.

Publications

Published literature highly relevant to the biological target of this product and referencing this antibody or clone are retrieved from PubMed database provided by The United States National Library of Medicine at the National Institutes of Health.