Weight | 1 lbs |
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Dimensions | 9 × 5 × 2 in |
accession | Q7TQH7 |
express system | HEK293 |
product tag | C-His |
purity | > 95% as determined by Tris-Bis PAGE;> 95% as determined by HPLC |
background | LDL receptor-related protein (LRP) 10 was recently identified as a Parkinson's disease gene through genome-wide linkage and sequencing analysis, but its role in Parkinson's disease in various populations is still unclear. |
molecular weight | The protein has a predicted MW of 46.88 kDa. Due to glycosylation, the protein migrates to 55-62 kDa based on Tris-Bis PAGE result. |
available size | 100 µg, 500 µg |
endotoxin | Less than 1EU per μg by the LAL method. |
Mouse LRP10 Protein 2888
$270.00 – $900.00
Summary
- Expression: HEK293
- Pure: Yes (HPLC)
- Amino Acid Range: Arg18-Lys441
Mouse LRP10 Protein 2888
protein |
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Size and concentration 100, 500µg and lyophilized |
Form Lyophilized |
Storage Instructions Valid for 12 months from date of receipt when stored at -80°C. Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles. |
Storage buffer Shipped at ambient temperature. |
Purity > 95% as determined by Tris-Bis PAGE |
target relevance |
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LDL receptor-related protein (LRP) 10 was recently identified as a Parkinson's disease gene through genome-wide linkage and sequencing analysis, but its role in Parkinson's disease in various populations is still unclear. |
Protein names Low-density lipoprotein receptor-related protein 10 (LRP-10) |
Gene names Lrp10,Lrp10 Lrp9 |
Protein family LDLR family |
Mass 10090Da |
Function Probable receptor, which is involved in the internalization of lipophilic molecules and/or signal transduction. May be involved in the uptake of lipoprotein APOE in liver. |
Subellular location Membrane ; Single-pass type I membrane protein. Membrane, coated pit . |
Tissues Highly expressed in heart, lung, liver and liver. Expressed at low level in brain and spleen. Weakly or not expressed in testis and skeletal muscle. In liver, it is expressed in hepatocytes and at higher level in sinusoidal lining. In the kidney, it is expressed in peritubular capillaries. In brain, it is expressed in the epithelium of the choroid plexus ependymal cells of the third ventricle pia matter, and to lesser extent in hippocampal fields CA2 and CA3. |
Target Relevance information above includes information from UniProt accession: Q7TQH7 |
The UniProt Consortium |
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The purity of Mouse LRP10 is greater than 95% as determined by SEC-HPLC. |
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Mouse LRP10 on Tris-Bis PAGE under reduced condition. The purity is greater than 95%. |
Publications
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