| Weight | 1 lbs |
|---|---|
| Dimensions | 9 × 5 × 2 in |
| accession | A0A2K5VQG9 |
| express system | HEK293 |
| product tag | C-His |
| purity | > 95% as determined by Tris-Bis PAGE;> 95% as determined by HPLC |
| background | CA9 is a member of the carbonic anhydrases' family, that is often expressed in cancer cells under hypoxic condition. CA9 expression potentially contributes to the regulation of cancer cell differentiation and mediates tumour-associated genes and signalling pathways, including apoptosis, hypoxia, G2M checkpoint, PI3K/AKR/mTOR signalling and TGF-beta signalling pathways. |
| molecular weight | The protein has a predicted MW of 41.03 kDa. Due to glycosylation, the protein migrates to 50-60 kDa based on Tris-Bis PAGE result. |
| available size | 100 µg, 500 µg |
| endotoxin | Less than 1EU per μg by the LAL method. |
Cynomolgus CA9/Carbonic Anhydrase IX Protein 2768
$315.00 – $1,050.00
Summary
- Expression: HEK293
- Active: Yes (catalytic)
- Amino Acid Range: Gln38-Asp402
Cynomolgus CA9/Carbonic Anhydrase IX Protein 2768
| protein |
|---|
| Size and concentration 100, 500µg and lyophilized |
| Form Lyophilized |
| Storage Instructions Valid for 12 months from date of receipt when stored at -80°C. Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles. |
| Storage buffer Shipped at ambient temperature. |
| Purity > 95% as determined by Tris-Bis PAGE |
| target relevance |
|---|
| CA9 is a member of the carbonic anhydrases' family, that is often expressed in cancer cells under hypoxic condition. CA9 expression potentially contributes to the regulation of cancer cell differentiation and mediates tumour-associated genes and signalling pathways, including apoptosis, hypoxia, G2M checkpoint, PI3K/AKR/mTOR signalling and TGF-beta signalling pathways. |
| Protein names Carbonic anhydrase (EC 4.2.1.1) |
| Gene names CA9,CA9 |
| Protein family Alpha-carbonic anhydrase family |
| Mass 9541Da |
| Function Reversible hydration of carbon dioxide. |
| Target Relevance information above includes information from UniProt accession: A0A2K5VQG9 |
| The UniProt Consortium |
