ELISA with Cynomolgus Integrin alpha V beta 3 (ITGAV&ITGB3) Heterodimer 2576

HPLC of Cynomolgus Integrin alpha V beta 3 (ITGAV&ITGB3) Heterodimer Pr 2576

SDS-PAGE gel of Cynomolgus Integrin alpha V beta 3 (ITGAV&ITGB3) Hetero 2576

Cynomolgus Integrin alpha V beta 3 (ITGAV&ITGB3) Heterodimer Protein 2576

$1,250.00

Summary

Expression: HEK293
Functional: Yes (ELISA)
Amino Acid Range: Phe31-Pro993(ITGAV)acidic tail & Gly27-Asp718(ITGB3)basic tail

SKU: 2576parent Categories: proteins, Recombinant proteins Tag: active proteins

Weight	1 lbs
Dimensions	9 × 5 × 2 in
accession	A0A2K5WCD3(ITGAV)&A0A2K5WYN9(ITGB3)
express system	HEK293
product tag	C-His
purity	> 95% as determined by Tris-Bis PAGE;> 95% as determined by HPLC
background	ITGAV&ITGB3 binds to NRG1 (via EGF domain) and this binding is essential for NRG1-ERBB signaling. ITGAV&ITGB3 binds to FGF1 and this binding is essential for FGF1 signaling. ITGAV&ITGB3 binds to FGF2 and this binding is essential for FGF2 signaling. ITGAV&ITGB3 binds to IGF1 and this binding is essential for IGF1 signaling. ITGAV&ITGB3 binds to IGF2 and this binding is essential for IGF2 signaling.
molecular weight	The protein has a predicted MW of 112.31 kDa (ITGAV) & 81.27 kDa (ITGB3). Due to glycosylation, the protein migrates 95-140 to kDa based on Tris-Bis PAGE result.
available size	100 µg, 500 µg
endotoxin	Less than 1EU per μg by the LAL method.

Cynomolgus Integrin alpha V beta 3 (ITGAV&ITGB3) Heterodimer Protein 2576

protein

Size and concentration 100, 500µg and lyophilized
Form Lyophilized
Storage Instructions Valid for 12 months from date of receipt when stored at -80°C. Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
Storage buffer Shipped at ambient temperature.
Purity > 95% as determined by Tris-Bis PAGE

target relevance
ITGAV&ITGB3 binds to NRG1 (via EGF domain) and this binding is essential for NRG1-ERBB signaling. ITGAV&ITGB3 binds to FGF1 and this binding is essential for FGF1 signaling. ITGAV&ITGB3 binds to FGF2 and this binding is essential for FGF2 signaling. ITGAV&ITGB3 binds to IGF1 and this binding is essential for IGF1 signaling. ITGAV&ITGB3 binds to IGF2 and this binding is essential for IGF2 signaling.
Protein names Integrin subunit alpha V
Gene names ITGAV,ITGAV
Protein family Integrin alpha chain family
Mass 115993Da
Subellular location Membrane ; Single-pass type I membrane protein .
Target Relevance information above includes information from UniProt accession: A0A2K5WCD3
The UniProt Consortium

Data

ELISA with Cynomolgus Integrin alpha V beta 3 (ITGAV&ITGB3) Heterodimer

Immobilized Cynomolgus ITGAV&ITGB3, His Tag at 0.5µg/ml (100µl/Well) on the plate. Dose response curve for Anti-alpha V beta 3 Antibody, hFc Tag with the EC50 of 10.1ng/ml determined by ELISA.

HPLC of Cynomolgus Integrin alpha V beta 3 (ITGAV&ITGB3) Heterodimer Pr

The purity of Cynomolgus ITGAV&ITGB3 is greater than 95% as determined by SEC-HPLC.

SDS-PAGE gel of Cynomolgus Integrin alpha V beta 3 (ITGAV&ITGB3) Hetero

Cynomolgus ITGAV&ITGB3 on Tris-Bis PAGE under reduced condition. The purity is greater than 95%.

Publications

Published literature highly relevant to the biological target of this product and referencing this antibody or clone are retrieved from PubMed database provided by The United States National Library of Medicine at the National Institutes of Health.