Human HLA-A*02:01&B2M&PRAME (ALYVDSLFFL) Monomer Protein 2486

$310.00 – $1,125.00

Summary

Expression: HEK293
Functional: Yes (ELISA)
Amino Acid Range: Gly25-Thr305(HLA-A*02:01), Ile21-Met119(B2M) and ALYVDSLFFL peptide

available size

Clear

SKU: 2486parent Categories: proteins, Recombinant proteins Tag: active proteins

Weight	1 lbs
Dimensions	9 × 5 × 2 in
accession	P79603(HLA-A*02:01)&P61769(B2M)&ALYVDSLFFL
express system	HEK293
product tag	C-His-Avi
purity	> 95% as determined by Tris-Bis PAGE;> 95% as determined by HPLC
background	PRAME (PReferentially expressed Antigen in MElanoma) is a melanoma-associated antigen expressed in cutaneous and ocular melanomas and some other malignant neoplasms, while its expression in normal tissue and benign tumors is limited.
molecular weight	The protein has a predicted MW of 50.60 kDa. Due to glycosylation, the protein migrates to 53-63 kDa based on Tris-Bis PAGE result.
available size	100 µg, 500 µg
endotoxin	Less than 1EU per μg by the LAL method.

Human HLA-A*02:01&B2M&PRAME (ALYVDSLFFL) Monomer Protein 2486

protein

Size and concentration 100, 500µg and lyophilized
Form Lyophilized
Storage Instructions Valid for 12 months from date of receipt when stored at -80°C. Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
Storage buffer Shipped at ambient temperature.
Purity > 95% as determined by Tris-Bis PAGE

target relevance
PRAME (PReferentially expressed Antigen in MElanoma) is a melanoma-associated antigen expressed in cutaneous and ocular melanomas and some other malignant neoplasms, while its expression in normal tissue and benign tumors is limited.
Protein names MHC class I HLA-A protein (MHC class I antigen)
Gene names HLA-A02,HLA-A02 HLA-A
Protein family MHC class I family
Mass 9606Da
Target Relevance information above includes information from UniProt accession: P79603
The UniProt Consortium

Data

ELISA with Human HLA-A*02:01&B2M&PRAME (ALYVDSLFFL) Monomer Protein

Immobilized Human HLA-A*02:01&B2M&PRAME (ALYVDSLFFL) Monomer, His Tag at 5µg/ml (100µl/Well) on the plate. Dose response curve for Anti-HLA-A*02:01&B2M&PRAME (ALYVDSLFFL) Antibody, hFc Tag with the EC50 of 40.3ng/ml determined by ELISA.

HPLC of Human HLA-A*02:01&B2M&PRAME (ALYVDSLFFL) Monomer Protein

The purity of Human HLA-A*02:01&B2M&PRAME (ALYVDSLFFL) Monomer is greater than 95% as determined by SEC-HPLC.

SDS-PAGE gel of Human HLA-A*02:01&B2M&PRAME (ALYVDSLFFL) Monomer Protei

Human HLA-A*02:01&B2M&PRAME (ALYVDSLFFL) Monomer on Tris-Bis PAGE under reduced condition. The purity is greater than 95%.

Publications

pmid	title	authors	citation
We haven't added any publications to our database yet.

Published literature highly relevant to the biological target of this product and referencing this antibody or clone are retrieved from PubMed database provided by The United States National Library of Medicine at the National Institutes of Health.