Weight | 1 lbs |
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Dimensions | 9 × 5 × 2 in |
accession | F7FXB6 |
express system | HEK293 |
product tag | C-His |
purity | > 95% as determined by Tris-Bis PAGE; > 95% as determined by HPLC |
background | gp130 is a common signal transducing component of the functional receptor complexes for the interleukin (IL)-6 family of cytokines, ie, IL-6, IL-11, leukemia inhibitory factor (LIF), oncostatin M, ciliary neurotrophic factor, and cardiotrophin-1. These cytokines exhibit pleiotropic biological activities in, for instance, immune, hematopoietic, and neural systems, and function in a redundant manner owing to the shared usage of gp130. |
molecular weight | The protein has a predicted MW of 69.09 kDa. Due to glycosylation, the protein migrates to 75-105 kDa based on Tris-Bis PAGE result. |
available size | 100 µg, 500 µg |
endotoxin | Less than 1EU per μg by the LAL method. |
Rhesus macaque gp130/CD130/IL-6 R beta Protein 2482
$240.00 – $800.00
Summary
- Expression: HEK293
- Pure: Yes (HPLC)
- Amino Acid Range: Glu47-Ala644
Rhesus macaque gp130/CD130/IL-6 R beta Protein 2482
protein |
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Size and concentration 100, 500µg and lyophilized |
Form Lyophilized |
Storage Instructions Valid for 12 months from date of receipt when stored at -80°C. Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles. |
Storage buffer Shipped at ambient temperature. |
Purity > 95% as determined by Tris-Bis PAGE |
target relevance |
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gp130 is a common signal transducing component of the functional receptor complexes for the interleukin (IL)-6 family of cytokines, ie, IL-6, IL-11, leukemia inhibitory factor (LIF), oncostatin M, ciliary neurotrophic factor, and cardiotrophin-1. These cytokines exhibit pleiotropic biological activities in, for instance, immune, hematopoietic, and neural systems, and function in a redundant manner owing to the shared usage of gp130. |
Protein names Interleukin 6 cytokine family signal transducer |
Gene names IL6ST,IL6ST |
Protein family Type I cytokine receptor family, Type 2 subfamily |
Mass 9544Da |
Subellular location Membrane ; Single-pass type I membrane protein . |
Target Relevance information above includes information from UniProt accession: F7FXB6 |
The UniProt Consortium |
Data
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The purity of Rhesus macaque gp130 is greater than 95% as determined by SEC-HPLC. |
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Rhesus macaque gp130 on Tris-Bis PAGE under reduced condition. The purity is greater than 95%. |
Publications
Publications
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Protocols
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