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Human HLA-A*11:01&B2M&KRAS G12C (VVVGACGVGK) Tetramer Protein 5041

$750.00$3,000.00

Summary

  • Expression: HEK293
  • Pure: Yes (HPLC)
  • Amino Acid Range: Gly25-Thr305(HLA-A*11:01), Ile21-Met119(B2M) and VVVGACGVGK peptide
SKU: 5041parent Categories: , Tag:
Weight 1 lbs
Dimensions 9 × 5 × 2 in
accession

AAV53343(HLA-A*11:01)&P61769(B2M)&VVVGACGVGK

express system

HEK293

product tag

C-His-Avi

purity

> 95% as determined by Tris-Bis PAGE;> 90% as determined by HPLC

background

Kirsten rat sarcoma 2 viral oncogene homolog (KRAS) is the most commonly mutated oncogene in human cancer. The developments of many cancers depend on sustained expression and signaling of KRAS, which makes KRAS a high-priority therapeutic target. The virtual screening approach to discover novel KRAS inhibitors and synthetic lethality interactors of KRAS are discussed in detail.

molecular weight

The protein has a predicted MW of 258 kDa. Due to glycosylation, the protein migrates to 260-265 kDa under Non reducing (N) condition based on Tris-Bis PAGE result.

available size

100 µg, 500 µg

endotoxin

Less than 1EU per μg by the LAL method.

Human HLA-A*11:01&B2M&KRAS G12C (VVVGACGVGK) Tetramer Protein 5041

protein
Size and concentration
100, 500µg and lyophilized
Form
Lyophilized
Storage Instructions
Valid for 12 months from date of receipt when stored at -80°C. Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
Storage buffer
Shipped at ambient temperature.
Purity
> 95% as determined by Tris-Bis PAGE
No information
target relevance

Data

HPLC of Human HLA-A*11:01&B2M&KRAS G12C (VVVGACGVGK) Tetramer Protein
The purity of Human HLA-A*11:01&B2M&KRAS G12C (VVVGACGVGK) Tetramer is greater than 90% as determined by SEC-HPLC.
SDS-PAGE gel of Human HLA-A*11:01&B2M&KRAS G12C (VVVGACGVGK) Tetramer P
Human HLA-A*11:01&B2M&KRAS G12C (VVVGACGVGK) Tetramer Protein on Tris-Bis PAGE under Non reducing (-) condition. The purity is greater than 95%.

Publications

Publications

pmid title authors citation
We haven't added any publications to our database yet.
Published literature highly relevant to the biological target of this product and referencing this antibody or clone are retrieved from PubMed database provided by The United States National Library of Medicine at the National Institutes of Health.

Protocols

relevant to this product

Documents

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