Mouse Qa-1b&B2M&Qdm (AMAPRTLLL) Monomer Protein 5033

$310.00 – $1,125.00

Summary

Expression: HEK293
Pure: Yes (HPLC)
Amino Acid Range: His23-Pro296(Qa-1b), Ile21-Met119(B2M) and AMAPRTLLL peptide

SKU: 5033parent Categories: proteins, Recombinant proteins Tag: active proteins

Weight	1 lbs
Dimensions	9 × 5 × 2 in
accession	P06339(Q1b)&P01887(B2M)&AMAPRTLLL
express system	HEK293
product tag	C-His-Avi
purity	> 95% as determined by Tris-Bis PAGE;> 95% as determined by HPLC
background	Qa-1b binds a peptide (AMAPRTLLL), referred to as Qdm (for Qa-1 determinant modifier), derived from the signal sequence of murine class Ia molecules. This peptide binds with high affinity and accounts for almost all of the peptides associated with this molecule. Human histocompatibility leukocyte antigen (HLA)-E, a homologue of Qa-1b, binds similar peptides derived from human class Ia molecules and interacts with CD94/NKG2 receptors on natural killer cells.
molecular weight	The protein has a predicted MW of 50.60 kDa. Due to glycosylation, the protein migrates to 55-65 kDa based on Tris-Bis PAGE result.
available size	100 µg, 500 µg
endotoxin	Less than 1EU per μg by the LAL method.

Mouse Qa-1b&B2M&Qdm (AMAPRTLLL) Monomer Protein 5033

protein

Size and concentration 100, 500µg and lyophilized
Form Lyophilized
Storage Instructions Valid for 12 months from date of receipt when stored at -80°C. Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
Storage buffer Shipped at ambient temperature.
Purity > 95% as determined by Tris-Bis PAGE

target relevance
Qa-1b binds a peptide (AMAPRTLLL), referred to as Qdm (for Qa-1 determinant modifier), derived from the signal sequence of murine class Ia molecules. This peptide binds with high affinity and accounts for almost all of the peptides associated with this molecule. Human histocompatibility leukocyte antigen (HLA)-E, a homologue of Qa-1b, binds similar peptides derived from human class Ia molecules and interacts with CD94/NKG2 receptors on natural killer cells.
Protein names H-2 class I histocompatibility antigen, D-37 alpha chain
Gene names H2-T23,H2-T23
Protein family MHC class I family
Mass 40875Da
Function Involved in the presentation of foreign antigens to the immune system.
Subellular location Membrane; Single-pass type I membrane protein.
Structure Heterodimer of an alpha chain and a beta chain (beta-2-microglobulin).
Target Relevance information above includes information from UniProt accession: P06339
The UniProt Consortium

HPLC of Mouse Qa-1b&B2M&Qdm (AMAPRTLLL) Monomer Protein

The purity of Mouse Qa-1b&B2M&Qdm (AMAPRTLLL) Monomer is greater than 95% as determined by SEC-HPLC.

SDS-PAGE gel of Mouse Qa-1b&B2M&Qdm (AMAPRTLLL) Monomer Protein

Mouse Qa-1b&B2M&Qdm (AMAPRTLLL) Monomer on Tris-Bis PAGE under reduced condition. The purity is greater than 95%.

Publications

pmid	title	authors	citation
We haven't added any publications to our database yet.

Published literature highly relevant to the biological target of this product and referencing this antibody or clone are retrieved from PubMed database provided by The United States National Library of Medicine at the National Institutes of Health.