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Biotinylated Cynomolgus/Rhesus macaque LRRC15/LIB Protein 2204

$525.00$1,750.00

Summary

  • Expression: HEK293
  • Functional: Yes (ELISA)
  • Amino Acid Range: Tyr22-Gly538
SKU: 2204parent Categories: , Tag:
Weight 1 lbs
Dimensions 9 × 5 × 2 in
express system

HEK293

product tag

C-His-Avi

purity

> 95% as determined by Tris-Bis PAGE;> 95% as determined by HPLC

background

The chimeric protein binds in vitro and in vivo to a specific element upstream of LRRC15, leading to dramatic transcriptional activation.  LRRC15 encodes a leucine-rich transmembrane protein, present at the leading edge of migrating cells, the expression of which in normal tissues is restricted to the invasive cytotrophoblast layer of the placenta; small interfering (siRNA)-mediated suppression of LRRC15 expression in breast cancer cells leads to abrogation of invasiveness in vitro.

molecular weight

The protein has a predicted MW of 61.50 kDa. Due to glycosylation, the protein migrates to 70-90 kDa based on Tris-Bis PAGE result.

available size

100 µg, 500 µg

endotoxin

Less than 1EU per μg by the LAL method.

Biotinylated Cynomolgus/Rhesus macaque LRRC15/LIB Protein 2204

protein
Size and concentration
100, 500µg and lyophilized
Form
Lyophilized
Storage Instructions
Valid for 12 months from date of receipt when stored at -80°C. Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
Storage buffer
Shipped at ambient temperature.
Purity
> 95% as determined by Tris-Bis PAGE
No information
target relevance

Data

ELISA with Biotinylated Cynomolgus/Rhesus macaque LRRC15/LIB Protein
Immobilized Anti-LRRC15 Antibody, hFc Tag at 5µg/ml (100µl/Well) on the plate. Dose response curve for Biotinylated Cynomolgus/Rhesus macaque LRRC15, His Tag with the EC50 of 75.9ng/ml determined by ELISA.
HPLC of Biotinylated Cynomolgus/Rhesus macaque LRRC15/LIB Protein
The purity of Biotinylated Cynomolgus/Rhesus macaque LRRC15 is greater than 95% as determined by SEC-HPLC.
SDS-PAGE gel of Biotinylated Cynomolgus/Rhesus macaque LRRC15/LIB Prote
Biotinylated Cynomolgus/Rhesus macaque LRRC15 on Tris-Bis PAGE under reduced condition. The purity is greater than 95%.

Publications

Publications

pmid title authors citation
We haven't added any publications to our database yet.
Published literature highly relevant to the biological target of this product and referencing this antibody or clone are retrieved from PubMed database provided by The United States National Library of Medicine at the National Institutes of Health.

Protocols

relevant to this product

Documents

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