Immunohistochemistry (IHC) : Human thyroid tissue stained with anti-CD34 antibody using peroxidase-conjugate and DAB chromogen. Note the cytoplasmic staining of vascular endothelial cells.

mouse anti-CD34 monoclonal antibody (QBEnd-10) 6088

Price range: $160.00 through $528.00

Antibody summary

Mouse monoclonal to CD34
Suitable for: Immunohistochemistry (formalin-fixed, paraffin-embedded tissues)
Reacts with: Human
Isotype:IgG1
Control: Hemangioma
Visualization: Cell membrane/cytoplasmic
0.1, 0.5, 1.0 mL concentrated, 7 mL prediluted

available sizes

Clear

SKU: 6088parent Category: antibody Tags: anatomy, CD34, Vascular Markers

Weight	1 lbs
Dimensions	9 × 5 × 2 in
host	mouse
isotype	IgG1
clonality	monoclonal
concentration	concentrate, predilute
applications	IHC
reactivity	human
available size	0.1 mL, 0.5 mL, 1 mL concentrated, 7 mL prediluted

mouse anti-CD34 monoclonal antibody QBEnd-10 6088

antibody
Database link: human P28906
Tested applications IHC
Recommended dilutions Concentrated 1:100-200
Application Notes Positive control: Hemangioma
Immunogen Detergent solubilized vesicular suspension prepared from a perfusate of human term placenta
Size and concentration 7 mL prediluted or 0.1, 0.5, 1.0 mL and concentrated
Form liquid
Storage Instructions 2-8°C for short term, for longer term at -20°C. Avoid freeze / thaw cycles.
Purity affinity purified
Clonality monoclonal
Isotype IgG1
Compatible secondaries goat anti-mouse IgG, H&L chain specific, peroxidase conjugated polyclonal antibody 5486 goat anti-mouse IgG, H&L chain specific, biotin conjugated, Conjugate polyclonal antibody 2685 goat anti-mouse IgG, H&L chain specific, FITC conjugated polyclonal antibody 7854 goat anti-mouse IgG, H&L chain specific, peroxidase conjugated polyclonal antibody, crossabsorbed 1706 goat anti-mouse IgG, H&L chain specific, biotin conjugated polyclonal antibody, crossabsorbed 1716 goat anti-mouse IgG, H&L chain specific, FITC conjugated polyclonal antibody, crossabsorbed 1721
Isotype control Mouse monoclonal IgG1 - Isotype Control

target relevance
Protein names Hematopoietic progenitor cell antigen CD34 (CD antigen CD34)
Gene names CD34,CD34
Protein family CD34 family
Mass 40716Da
Function FUNCTION: Possible adhesion molecule with a role in early hematopoiesis by mediating the attachment of stem cells to the bone marrow extracellular matrix or directly to stromal cells. Could act as a scaffold for the attachment of lineage specific glycans, allowing stem cells to bind to lectins expressed by stromal cells or other marrow components. Presents carbohydrate ligands to selectins.
Subellular location SUBCELLULAR LOCATION: Membrane; Single-pass type I membrane protein.
Tissues TISSUE SPECIFICITY: Selectively expressed on hematopoietic progenitor cells and the small vessel endothelium of a variety of tissues.
Post-translational modification PTM: Highly glycosylated.; PTM: Phosphorylated on serine residues by PKC. {ECO:0000269\|PubMed:1694174}.
Target Relevance information above includes information from UniProt accession: P28906
The UniProt Consortium

Data

Human thyroid tissue stained with anti-CD34 antibody using peroxidase-conjugate and DAB chromogen. Note the cytoplasmic staining of vascular endothelial cells.

Publications

pmid	title	authors	citation
We haven't added any publications to our database yet.

Published literature highly relevant to the biological target of this product and referencing this antibody or clone are retrieved from the PubMed database provided by the United States National Library of Medicine at the National Institutes of Health.