Monkeypox virus M1R Protein 7006

Price range: $283.00 through $3,200.00

Summary

Expression: Mammalian
Pure: Yes (HPLC)
Amino Acid Range: Gly2-Gly183

available size

Clear

SKU: 7006parent Categories: proteins, Recombinant proteins Tag: mpox (monkeypox virus)

Weight	1 lbs
Dimensions	9 × 5 × 2 in
accession	NP_536507.1
express system	Mammalian
product tag	C-FLAG
purity	> 95% as determined by Tris-Bis PAGE;> 95% as determined by HPLC
background	Monkeypox is a zoonotic disease caused by monkeypox virus (MPXV), which is a member of orthopoxvirus genus. M1R is homologous to the vaccinia virus L1 protein, a transmembrane protein found on the surface of mature IMV particles. Encoded by the L1R ORF, it is highly conserved, participates in virion assembly, and plays an important role in viral entry and maturation. L1 is required for induction of cell-cell fusion at low pH and is critical for vaccinia virus replication. Co-immunoprecipitation experiments showed that L1 interacts with A28 or some other components of the entry/fusion complex (EFC), and indirectly with F9, suggesting that L1 is an additional component of the viral entry apparatus. L1-MVs can attach to cells but cannot enter or induce membrane fusion. L1 physically interacts with EFC and interacts with other known entry protein synergy.L1R is a myristoylated protein responsible for virion assembly and being present on intracellular mature virion (IMV) surface, it is also a potent target for eliciting neutralizing antibodies.
molecular weight	20.1 kDa
available size	1000 µg, 50 µg, 500 µg

Monkeypox M1R Protein 7006

antibody

Tested applications WB,ELISA
Size and concentration 50, 500, 1000µg and 1 mg/mL
Storage buffer Supplied as a 0.2 µm filtered solution of PBS, pH7.4.
Purity > 95% as determined by SDS-PAGE

target relevance

human antibody anti-Monkeypox Virus (mpox)

Data

SDSPAGE Protein purity

FAQ & Publications

Frequently Asked Questions

What expression system is used for the production of the Monkeypox virus M1R Protein 7006?

The Monkeypox virus M1R Protein 7006 is produced using a mammalian expression system.

Which applications has the Monkeypox virus M1R Protein 7006 been tested in?

This protein has been validated for use in Western blot (WB) and enzyme-linked immunosorbent assay (ELISA) applications.

How is the Monkeypox virus M1R Protein 7006 supplied and stored?

The protein is supplied as a 0.2 µm filtered solution in PBS buffer at pH 7.4, with a concentration of 1 mg/mL, and should be stored accordingly to maintain stability.

What is the purity level of the Monkeypox virus M1R Protein 7006, and how is it determined?

The protein purity is greater than 95%, as determined by both SDS-PAGE and HPLC analysis.

Publications

pmid	title	authors	citation
We haven't added any publications to our database yet.

Published literature highly relevant to the biological target of this product and referencing this antibody or clone are retrieved from the PubMed database provided by the United States National Library of Medicine at the National Institutes of Health.