Monkeypox virus E8L Protein 7007

Price range: $283.00 through $3,200.00

Summary

Expression: Mammalian
Pure: Yes (HPLC)
Amino Acid Range: Met1-Thr275

available size

Clear

SKU: 7007parent Categories: proteins, Recombinant proteins Tag: mpox (monkeypox virus)

Weight	1 lbs
Dimensions	9 × 5 × 2 in
accession	AIE40718.1
express system	Mammalian
product tag	C-FLAG
purity	> 95% as determined by Tris-Bis PAGE;> 95% as determined by HPLC
background	Monkeypox is a zoonotic disease caused by monkeypox virus (MPXV), which is a member of orthopoxvirus genus. The MPXV E8L protein is the homologous protein of vaccinia virus D8L, D8L protein binds to chondroitin sulfate (CS) on cells, revealing a different type of virus-GAG interaction.The D8L protein has also been shown to elicit strong humoral and cellular immune responses in mice. This abundant 32-kDa IMV protein plays an important role in virus entry and adsorption due to its ability to bind to chondroitin sulfate on host cells. In vitro, antibodies directed against D8L have IMV-neutralizing activity, and soluble D8L protein inhibits the adsorption of wild-type vaccinia virus to cells. In vivo, D8L is immunogenic, and immunization of mice with a DNA vaccine encoding D8L provides partial protection from lethal vaccinia virus challenge. A study by Sakhatskyy has confirmed that D8L induces strong protective antibody responses in vivo and improves the efficacy of polyvalent poxvirus DNA vaccines composed of A27L and B5R or of A27L, B5R, L1R, and A33R
molecular weight	32.7 kDa
available size	1000 µg, 50 µg, 500 µg

Monkeypox E8L Protein 7007

antibody

Tested applications WB,ELISA
Size and concentration 50, 500, 1000µg and 1 mg/mL
Storage buffer Supplied as a 0.2 µm filtered solution of PBS, pH7.4.
Purity > 95% as determined by SDS-PAGE

target relevance

human antibody anti-Monkeypox Virus (mpox)

Data

SDSPAGE Protein purity

FAQ & Publications

Frequently Asked Questions

What are the recommended applications for the Monkeypox virus E8L Protein 7007?

The Monkeypox virus E8L Protein 7007 is validated for use in Western blot (WB) and enzyme-linked immunosorbent assay (ELISA) applications.

How is the Monkeypox virus E8L Protein 7007 supplied and what is its purity level?

This protein is supplied as a 0.2 µm filtered solution in PBS buffer at pH 7.4, with a concentration of 1 mg/mL. The purity is greater than 95%, as determined by SDS-PAGE and HPLC analyses.

Publications

pmid	title	authors	citation
We haven't added any publications to our database yet.

Published literature highly relevant to the biological target of this product and referencing this antibody or clone are retrieved from the PubMed database provided by the United States National Library of Medicine at the National Institutes of Health.