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Monkeypox virus A29L Protein 7008

Price range: $209.00 through $2,200.00

Summary

  • Expression: Mammalian
  • Pure: Yes (HPLC)
  • Amino Acid Range: Ser21-Glu110
SKU: 7008parent Categories: , Tag:
Weight 1 lbs
Dimensions 9 × 5 × 2 in
accession

AAP48865.1

express system

Mammalian

product tag

C-FLAG

purity

> 95% as determined by Tris-Bis PAGE;> 95% as determined by HPLC

background

Monkeypox is a zoonotic disease caused by monkeypox virus (MPXV), which is a member of orthopoxvirus genus. A29L is an intracellular mature virus (IMV) surface envelope protein that is homologous to vaccinia virus (VACV) A27 and is widely conserved in the Poxviridae family. The A27L protein (p14) is a multifunctional protein that has been implicated in virus attachment, virus–cell fusion, cell–cell fusion, plaque size, and the formation of enveloped virions. The involvement of A27 in mature virus (IMV) inhibits the assembly of fusion protein A26. After MVs are endocytosed by vesicles, the acidic endocytic environment activates the dissociation of A26 protein from MVs, resulting in fusion of the viral membrane with the vesicle membrane. A27 interacts with the integral membrane protein A17, and then forms a protein complex with A26 through disulfide bond linkage to anchor the A26 protein to mature virus (MV) particles.

molecular weight

11.4 kDa

available size

1000 µg, 50 µg, 500 µg

Monkeypox A29L Protein 7008

antibody
Tested applications
WB,ELISA
Size and concentration
50, 500, 1000µg and 1 mg/mL
Storage buffer
Supplied as a 0.2 µm filtered solution of PBS, 300mM NaCl, pH7.4.
Purity
> 95% as determined by SDS-PAGE
target relevance
human antibody anti-Monkeypox Virus (mpox)

Data

SDSPAGE Protein purity

FAQ & Publications

Frequently Asked Questions
What expression system is used for producing the Monkeypox virus A29L Protein 7008?
The Monkeypox virus A29L Protein 7008 is expressed in a mammalian expression system.
Which laboratory techniques has the Monkeypox A29L Protein 7008 been validated for?
This protein has been tested and validated for use in Western blotting (WB) and enzyme-linked immunosorbent assay (ELISA) applications.
What is the purity level of the Monkeypox virus A29L Protein 7008 and how is it determined?
The protein purity is greater than 95%, as determined by both SDS-PAGE and high-performance liquid chromatography (HPLC).
In what buffer and concentration is the Monkeypox A29L Protein 7008 supplied?
The protein is supplied as a 0.2 µm filtered solution containing PBS and 300 mM NaCl at pH 7.4, with a concentration of 1 mg/mL.
What is the molecular weight and amino acid range of the Monkeypox virus A29L Protein 7008?
The protein has a molecular weight of approximately 11.4 kDa and includes the amino acid sequence from Ser21 to Glu110.
Publications
pmid title authors citation
We haven't added any publications to our database yet.

Published literature highly relevant to the biological target of this product and referencing this antibody or clone are retrieved from the PubMed database provided by the United States National Library of Medicine at the National Institutes of Health.

Protocols

relevant to this product
ELISA

Documents

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