| Weight | 1 lbs |
|---|---|
| Dimensions | 9 × 5 × 2 in |
| accession | AAP48865.1 |
| express system | Mammalian |
| product tag | C-FLAG |
| purity | > 95% as determined by Tris-Bis PAGE;> 95% as determined by HPLC |
| background | Monkeypox is a zoonotic disease caused by monkeypox virus (MPXV), which is a member of orthopoxvirus genus. A29L is an intracellular mature virus (IMV) surface envelope protein that is homologous to vaccinia virus (VACV) A27 and is widely conserved in the Poxviridae family. The A27L protein (p14) is a multifunctional protein that has been implicated in virus attachment, virus–cell fusion, cell–cell fusion, plaque size, and the formation of enveloped virions. The involvement of A27 in mature virus (IMV) inhibits the assembly of fusion protein A26. After MVs are endocytosed by vesicles, the acidic endocytic environment activates the dissociation of A26 protein from MVs, resulting in fusion of the viral membrane with the vesicle membrane. A27 interacts with the integral membrane protein A17, and then forms a protein complex with A26 through disulfide bond linkage to anchor the A26 protein to mature virus (MV) particles. |
| molecular weight | 11.4 kDa |
| available size | 1000 µg, 50 µg, 500 µg |
Monkeypox virus A29L Protein 7008
Price range: $209.00 through $2,200.00
Summary
- Expression: Mammalian
- Pure: Yes (HPLC)
- Amino Acid Range: Ser21-Glu110
Monkeypox A29L Protein 7008
| antibody |
|---|
| Tested applications WB,ELISA |
| Size and concentration 50, 500, 1000µg and 1 mg/mL |
| Storage buffer Supplied as a 0.2 µm filtered solution of PBS, 300mM NaCl, pH7.4. |
| Purity > 95% as determined by SDS-PAGE |
| target relevance |
|---|
| human antibody anti-Monkeypox Virus (mpox) |
FAQ & Publications
Frequently Asked Questions
What expression system is used for producing the Monkeypox virus A29L Protein 7008?
The Monkeypox virus A29L Protein 7008 is expressed in a mammalian expression system.
Which laboratory techniques has the Monkeypox A29L Protein 7008 been validated for?
This protein has been tested and validated for use in Western blotting (WB) and enzyme-linked immunosorbent assay (ELISA) applications.
What is the purity level of the Monkeypox virus A29L Protein 7008 and how is it determined?
The protein purity is greater than 95%, as determined by both SDS-PAGE and high-performance liquid chromatography (HPLC).
In what buffer and concentration is the Monkeypox A29L Protein 7008 supplied?
The protein is supplied as a 0.2 µm filtered solution containing PBS and 300 mM NaCl at pH 7.4, with a concentration of 1 mg/mL.
What is the molecular weight and amino acid range of the Monkeypox virus A29L Protein 7008?
The protein has a molecular weight of approximately 11.4 kDa and includes the amino acid sequence from Ser21 to Glu110.
Publications
| pmid | title | authors | citation |
|---|---|---|---|
| We haven't added any publications to our database yet. | |||
Published literature highly relevant to the biological target of this product and referencing this antibody or clone are retrieved from the PubMed database provided by the United States National Library of Medicine at the National Institutes of Health.
Protocols
| relevant to this product |
|---|
| ELISA |
Documents
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