Leishmania Human IgG Assay Control BC147G

$94.00

Summary

Virion/Serion Diagnostic Kit Control for research use (RUO)
Leishmania Human IgG Assay Control, recombinant
Applications: ELISA
Suitable for IgG detection
Ready-to-use; pre-diluted for SERION ELISA classic and SERION ELISA antigen assays
3 mL

SKU: BC147G Category: Virion/Serion kits Tags: ELISA control serum, IgG, Leishmania

Weight	1 lbs
Dimensions	9 × 5 × 2 in
target	Leishmania reactive IgG
species reactivity	Leishmania
applications	ELISA
assay type	Indirect & quantitative
available size	1 mL

Leishmania Human IgG Assay Control BC147G

kit
Research area Infectious Disease
Storage Store at 2-8°C.
Form liquid
Associated products Leishmania Human IgG Assay Control (BC147G) Leishmania IgG ELISA Kit (ESR147G)

target relevance

human antibody anti-Leishmania

Leishmania

Description
Protozoan parasite that causes leishmaniasis

Structure
Leishmania is a genus of obligate intracellular protozoan parasites belonging to the family Trypanosomatidae and the phylum Euglenozoa. More than twenty Leishmania species are known to cause human disease. The parasites have a complex life cycle involving phlebotomine sand flies as vectors and mammals, including humans, dogs, rodents, and other animals, as vertebrate hosts. Within the sand fly, Leishmania exists as motile promastigotes possessing a flagellum, whereas within mammalian hosts the parasite survives as non-flagellated amastigotes residing primarily within macrophages and other phagocytic cells. Leishmania species are endemic in tropical, subtropical, and Mediterranean regions worldwide and are responsible for a spectrum of diseases collectively known as leishmaniasis, ranging from localized skin lesions to life-threatening systemic infection.

Diagnosis
The diagnosis of leishmaniasis is performed through microscopic, molecular, serological, and culture-based methods. Direct microscopic examination of tissue aspirates, biopsies, bone marrow, lymph node samples, or skin lesions may reveal characteristic intracellular amastigotes within macrophages. Polymerase chain reaction (PCR) assays provide highly sensitive and specific detection of Leishmania DNA and are increasingly used for species identification and confirmation of infection. Serological assays, including ELISA, immunofluorescence, and rapid diagnostic tests based on recombinant antigens such as rK39, are widely used in the diagnosis of visceral leishmaniasis. Culture of parasites in specialized media may be performed in reference laboratories. Accurate species identification is important because disease manifestations, prognosis, and treatment options vary among Leishmania species.

Symptoms
Clinical manifestations of leishmaniasis depend on the infecting species and host immune response. Cutaneous leishmaniasis is the most common form and typically presents with one or more painless skin papules that gradually develop into chronic ulcers with raised borders. Mucocutaneous leishmaniasis may result in progressive destruction of the nasal, oral, and pharyngeal mucosa, causing severe disfigurement. Visceral leishmaniasis, also known as kala-azar, is the most severe form and is characterized by prolonged fever, weight loss, fatigue, anemia, hepatosplenomegaly, pancytopenia, and immune suppression. Without treatment, visceral leishmaniasis is frequently fatal. Post-kala-azar dermal leishmaniasis may develop after treatment of visceral disease and is characterized by persistent skin lesions containing parasites.

Data

FAQ & Publications

Frequently Asked Questions

What is the intended application of the Leishmania Human IgG Assay Control BC147G?

The Leishmania Human IgG Assay Control BC147G is designed for use in ELISA applications to detect Leishmania-specific human IgG antibodies.

How should the Leishmania Human IgG Assay Control BC147G be stored to maintain stability?

This assay control should be stored refrigerated at 2-8°C to ensure its stability and performance.

Is the Leishmania Human IgG Assay Control BC147G compatible with SERION ELISA kits?

Yes, the control is ready-to-use and pre-diluted specifically for compatibility with SERION ELISA classic and SERION ELISA antigen assays.

Publications

pmid	title	authors	citation
We haven't added any publications to our database yet.

Published literature highly relevant to the biological target of this product and referencing this antibody or clone are retrieved from the PubMed database provided by the United States National Library of Medicine at the National Institutes of Health.

Protocols

relevant to this product
BC147G protocol

Documents

#
CP0130	Safety Data Sheet	QC certificate

Reviews

There are no reviews yet.

Only logged in customers who have purchased this product may leave a review.

Leishmania Human IgG Assay Control BC147G

Data

FAQ & Publications

Protocols

Documents

Related Technical Resources & Posts

Reviews

Related Products

Cytomegalovirus IgG Control Serum BC109G

Brucella IgG Control Serum BC116G

Enterovirus IgG Control Serum BC133G

Borrelia burgdorferi IgG Control Serum BC121G

Echovirus IgG Control Serum BC135G

Bordetella pertussis IgG Control Serum BC120G

Echinococcus IgG Control Serum BC107G

Aspergillus fumigatus IgG Control Serum BC132G

Diphtheria IgG Control Serum BC130G

Adenovirus IgG Control Serum BC128G

Coxsackie IgG Virus Control Serum BC134G

Chlamydia trachomatis IgG Control Serum BC1372G

Chlamydia pneumoniae IgG Control Serum BC1371G

Candida albicans IgG Control Serum BC117G

Campylobacter jejuni IgG Control Serum BC139G