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Leishmania Human IgG Assay Control BC147G

$94.00

Summary

  • Virion/Serion Diagnostic Kit Control for research use (RUO)
  • Leishmania Human IgG Assay Control, recombinant
  • Applications: ELISA
  • Suitable for IgG detection
  • Ready-to-use; pre-diluted for SERION ELISA classic and SERION ELISA antigen assays
  • 3 mL
Weight1 lbs
Dimensions9 × 5 × 2 in
target

Leishmania reactive IgG

species reactivity

Leishmania

applications

ELISA

assay type

Indirect & quantitative

Available product – Leishmania Human IgG Assay Control BC147G

kit
Research area
Infectious Disease
Storage
Store at 2-8°C.
Form
liquid
Associated products
Leishmania Human IgG Assay Control (BC147G)
Leishmania IgG ELISA Kit (ESR147G)
target relevance
Organism
Leishmania species
Structure and strains
Leishmania is a parasitic protozoan, a single-celled organism of the genus Leishmania that is responsible for the disease leishmaniasis. They are spread by sandflies of the genus Phlebotomus in the Old World, and of the genus Lutzomyia in the New World. At least 93 sandfly species are proven or probable vectors worldwide. Their primary hosts are vertebrates; Leishmania commonly infects hyraxes, canids, rodents, and humans.
Disease
Leishmaniasis is an infectious disease caused by protozoic parasites of the genus Leishmania. The disease occurs predominantly in tropical and subtropical climate zones. Primarily affected are farm and domestic animals, however the disease can also be transmitted to humans. Leishmaniasis is distributed worldwide with high incidences in Eastern Africa, Southern America and Asia. In Europe, the Mediterranean area is particularly affected. Around 12 million people are infected with Leishmania worldwide.

caused by protozoic parasites of the genus Leishmania. The disease occurs predominantly in tropical and subtropical climate zones. Primarily affected are farm and domestic animals, however the disease can also be transmitted to humans. Leishmaniasis is distributed worldwide with high incidences in Eastern Africa, Southern America and Asia. In Europe, the Mediterranean area is particularly affected. Around 12 million people are infected with Leishmania worldwide. Disease Dogs and rodents serve as the main reservoirs for Leishmania, but also cats, horses, sheep and cattle may be afflicted. Sandflies (phlebotominae) or other moth flies (psychodidae) transmit the parasites to humans. The incubation period is very variable, ranging from a few weeks up to several years. Depending on the immune status, the various Leishmania species can induce different clinical manifestations, which are referred to as cutaneous, mucocutaneous or visceral leishmaniasis. Cutaneous leishmaniasis is frequently caused by L. tropica, L. major or L. aethiopica. Proliferation of the parasites is mainly restricted to the site of infection. Following an erythematous rash, a non-painful ulcer with a diameter of up to five centimeters can develop. Mucocutaneous leishmaniasis (uta, espundia) is caused by L. brasiliensis and affects - besides the skin - also the mucous membranes, e.g. in the nasal region, the oral cavity or the pharyngeal region, more seldom the genitals. The disease manifests clinically with severe skin ulceration and tissue destruction. Infections with L. donovani and - in Europe - L. infantum may induce visceral leishmaniasis (kala-azar). The disease manifests primarily with flu-like symptoms, swollen lymph nodes and recurring fever accompanied by abdominal pain, nausea, vomiting and diarrhea. Depending on the organs involved, additional clinical symptoms may occur.
Detection and diagnosis
Due to the variety of clinical presentations, the diagnosis of leishmaniasis is based on direct pathogen detection methods, such as cytology, histology or PCR, as well as on the serological determination of specific IgG antibodies by IFT or ELISA tests.

Data

Publications

Published literature highly relevant to the biological target of this product and referencing this antibody or clone are retrieved from PubMed database provided by The United States National Library of Medicine at the National Institutes of Health.




pmidtitleauthorscitation

Protocols

relevant to this product
BC147G protocol

Documents

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