FSME-TBE (Tick-Borne Encephalitis) Virus Antigen BA112VSL

$916.00

Summary

Virion/Serion Immunologics Antigen for research use (RUO)
FSME-TBE (Tick-Borne Encephalitis) Virus Antigen, recombinant
Suitable for detection of IgA, IgG & IgM antibodies in ELISA
Lot specific concentration, specified in mg/mL
1 mg

SKU: BA112VSL Category: Infectious disease proteins Tags: antigen, Tick-Borne Encephalitis Virus

Weight	1 lbs
Dimensions	9 × 5 × 2 in
target	FSME/TBE (Tick-Borne Encephalitis) Virus
species reactivity	Tick-Borne Encephalitis Virus (TBE/FSME)
applications	ELISA
assay type	Indirect & quantitative
available size	1 mg

FSME-TBE (Tick-Borne Encephalitis) Virus Antigen BA112VSL

kit
Research area Infectious Disease
Storage Store at -65°C or lower. Avoid repeated freeze-thaw cycles. Sonicate before use. 10 years from date of manufacture (under recommended storage conditions).
Form liquid
Associated products FSME/TBE (Tick-Borne Encephalitis) Virus (Premium) Antigen (BA112VS) FSME/TBE (Tick-Borne Encephalitis) Virus Antigen (BA112VSL) Tick-Borne Encephalitis Virus IgG Control Serum (BC112G) Tick-Borne Encephalitis Virus IgM Control Serum (BC112M) Tick-Borne Encephalitis Virus IgG ELISA Kit (ESR112G) Tick-Borne Encephalitis Virus IgM ELISA Kit (ESR112M)

target relevance
Tick-Borne Encephalitis Virus (TBE/FSME)
Description Virus that causes tick-borne encephalitis (TBE/FSME)
Structure Tick-borne encephalitis virus (TBEV), also known as FSME virus (Frühsommer-Meningoenzephalitis virus), is an enveloped, positive-sense, single-stranded RNA virus belonging to the genus Flavivirus within the family Flaviviridae. The virus is closely related to other medically important flaviviruses, including West Nile virus, Yellow fever virus, Dengue virus, and Zika virus. TBEV is maintained in nature through transmission cycles involving ixodid ticks, primarily Ixodes ricinus and Ixodes persulcatus, and a variety of wild mammalian hosts. Three major subtypes are recognized: European, Siberian, and Far Eastern. Human infection typically occurs through the bite of an infected tick, although transmission may also occur through the consumption of unpasteurized milk or dairy products from infected animals. The virus is neurotropic and can invade the central nervous system, resulting in severe neurological disease.
Diagnosis The diagnosis of tick-borne encephalitis virus infection is performed through serological and molecular methods. Detection of TBEV-specific IgM and IgG antibodies using ELISA is the primary laboratory approach and is considered highly sensitive and specific during the neurological phase of disease. Confirmation may be obtained using virus neutralization assays. Molecular detection by reverse transcription polymerase chain reaction (RT-PCR) may identify viral RNA during the early viremic phase but is often less useful after neurological symptoms develop because viremia is typically transient. Cerebrospinal fluid analysis frequently demonstrates pleocytosis and elevated protein concentrations in patients with central nervous system involvement. Accurate laboratory diagnosis is essential because clinical symptoms overlap with those of other viral and bacterial neurological infections.
Symptoms Tick-borne encephalitis virus infection frequently follows a biphasic course. After an incubation period of approximately seven to fourteen days, the initial phase is characterized by nonspecific flu-like symptoms including fever, fatigue, headache, muscle aches, malaise, and nausea. Following a symptom-free interval, a second phase may occur in which the virus affects the central nervous system, resulting in meningitis, encephalitis, meningoencephalitis, or myelitis. Neurological manifestations may include severe headache, neck stiffness, confusion, impaired consciousness, tremors, paralysis, seizures, and cognitive dysfunction. While many infections remain asymptomatic or mild, severe disease can result in long-term neurological sequelae or death, particularly among older adults and patients infected with more virulent viral subtypes.

Data

FAQ & Publications

Frequently Asked Questions

What is the recommended storage condition for the FSME-TBE Virus Antigen BA112VSL to ensure its stability?

The FSME-TBE Virus Antigen BA112VSL should be stored at -65°C or lower. It is important to avoid repeated freeze-thaw cycles and to sonicate the antigen before use to maintain its stability. Under these storage conditions, the antigen has a shelf life of 10 years from the date of manufacture.

For which immunoglobulin classes is the FSME-TBE Virus Antigen BA112VSL suitable for detection in ELISA assays?

The FSME-TBE Virus Antigen BA112VSL is suitable for the detection of IgA, IgG, and IgM antibodies in ELISA assays, enabling comprehensive serological analysis of Tick-Borne Encephalitis Virus infections.

Publications

pmid	title	authors	citation
We haven't added any publications to our database yet.

Published literature highly relevant to the biological target of this product and referencing this antibody or clone are retrieved from the PubMed database provided by the United States National Library of Medicine at the National Institutes of Health.