| Weight | 1 lbs |
|---|---|
| Dimensions | 9 × 5 × 2 in |
| target | Francisella tularensis reactive IgG |
| species reactivity | Francisella tularensis |
| applications | ELISA |
| assay type | Indirect & quantitative |
| available sizes | 96 tests |
Francisella tularensis IgG ELISA Kit ESR142G
$504.00
Summary
- Virion/Serion Diagnostic Kit for research use (RUO)
- Francisella tularensis IgG ELISA Kit
- Suitable for IgG detection
- Ready-to-use
- 96 tests
Francisella tularensis IgG ELISA Kit ESR142G
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| Assay type Indirect ELISA | ||||||||||||||||||
| Research area Infectious Disease | ||||||||||||||||||
| Sample type Serum, plasma, whole blood | ||||||||||||||||||
| Notes Pretreatment of samples with RF-Absorbent (Z200) is recommended for use with IgM ELISA kits to eliminate presence of sample rheumatoid factors and possible false negative results. | ||||||||||||||||||
Components
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| Storage Store at 2-8°C. | ||||||||||||||||||
| Associated products Francisella tularensis IgG ELISA Kit (ESR142G) Francisella tularensis IgM ELISA Kit (ESR142M) |
| target relevance |
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| Organism Francisella tularensis |
| Structure and strains Francisella tularensis is a pathogenic species of Gram-negative coccobacillus, an aerobic bacterium. It is nonspore-forming, nonmotile, and the causative agent of tularemia, the pneumonic form of which is often lethal without treatment. It is a fastidious, facultative intracellular bacterium, which requires cysteine for growth. Due to its low infectious dose, ease of spread by aerosol, and high virulence, F. tularensis is classified as a Tier 1 Select Agent by the U.S. government, along with other potential agents of bioterrorism such as Yersinia pestis, Bacillus anthracis, and Ebola virus. When found in nature, Francisella tularensis can survive for several weeks at low temperatures in animal carcasses, soil, and water. In the laboratory, F. tularensis appears as small rods (0.2 by 0.2 m), and is grown best at 35 37 °C. |
| Disease Tularemia is a zoonosis caused by the bacterium Francisella tularensis. Two types of Francisella tularensis can be distinguished epidemiologically, biochemically and genotypically: Francisella tularensis biovar tularensis (type A) is highly virulent. If left untreated, the infection has a high mortality. Francisella tularensis biovar holarctica (type B) is much less virulent but can also cause severe illness. The first symptoms of tularemia usually appear two to five days after the infection has occurred. Besides the classical general symptoms such as fever, malaise and joint and muscle pains, the clinical picture of tularemia can be very diverse. Inhalation of the pathogen often leads to a pulmonary manifestation (e. g. pneumonia) or to a septic, typhus-like illness. Infection through the digestive tract can cause vomiting, abdominal pain and diarrhoea. When identified promptly, tularemia can be treated effectively with antibiotics. |
| Detection and diagnosis Detection through culture from peripheral blood, swabs and biopsy material is difficult and can take several weeks. Since it is a highly infectious pathogen, such diagnostic tests are reserved for specialized laboratories. Serological diagnosis can be made by means of ELISA through the detection of specific antibodies. |
Data
Publications
Published literature highly relevant to the biological target of this product and referencing this antibody or clone are retrieved from PubMed database provided by The United States National Library of Medicine at the National Institutes of Health.| pmid | title | authors | citation |
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Protocols
| relevant to this product |
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| ESR142G protocol |
Documents
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