Chlamydia pneumoniae EB and RB Antigen BA1371VSER

$1,146.00

Summary

Virion/Serion Immunologics Antigen for research use (RUO)
Chlamydia pneumoniae EB and RB Antigen, recombinant
Suitable for detection of IgA, IgG & IgM antibodies in ELISA
Lot specific concentration, specified in mg/mL
1 mg

SKU: BA1371VSER Category: Infectious disease proteins Tags: antigen, Chlamydia

Weight	1 lbs
Dimensions	9 × 5 × 2 in
target	Chlamydia pneumoniae EB and RB
species reactivity	Chlamydia pneumoniae
applications	ELISA
assay type	Indirect & quantitative
available size	1 mg

Chlamydia pneumoniae EB and RB Antigen BA1371VSER

kit
Research area Infectious Disease
Storage Store at -65°C or lower. Avoid repeated freeze-thaw cycles. Sonicate before use. 10 years from date of manufacture (under recommended storage conditions).
Form liquid
Associated products Chlamydia trachomatis EB + RB Antigen (BA1372VSER) Chlamydia trachomatis MOMP Antigen (BA1372VSR2) Chlamydia trachomatis IgA Control Serum (BC1372A) Chlamydia trachomatis IgG Control Serum (BC1372G) Chlamydia trachomatis IgM Control Serum (BC1372M) Chlamydia trachomatis IgA ELISA Kit (ESR1372A) Chlamydia trachomatis IgG ELISA Kit (ESR1372G) Chlamydia trachomatis IgM ELISA Kit (ESR1372M) Chlamydia IgA ELISA Kit (ESR137A)

target relevance
Chlamydia pneumoniae
Description Bacterium that causes respiratory tract infections and atypical pneumonia
Structure Chlamydia pneumoniae is an obligate intracellular Gram-negative bacterium belonging to the family Chlamydiaceae. Like other Chlamydia species, it possesses a unique biphasic developmental cycle consisting of an infectious elementary body (EB) and a metabolically active reticulate body (RB). Elementary bodies are responsible for transmission and host cell invasion, whereas reticulate bodies replicate within membrane-bound intracellular inclusions. Chlamydia pneumoniae is a strictly human pathogen and is transmitted primarily through respiratory droplets. The organism infects epithelial cells and macrophages within the respiratory tract and is a common cause of community-acquired respiratory infections worldwide. Chronic or persistent infection has also been investigated for possible associations with atherosclerosis, asthma, and other chronic inflammatory conditions, although these relationships remain incompletely understood.
Diagnosis The diagnosis of Chlamydia pneumoniae infection is performed through molecular, serological, and microbiological methods. Polymerase chain reaction (PCR) assays are considered the most sensitive and specific diagnostic tools and allow direct detection of bacterial DNA in respiratory specimens. Serological testing using ELISA, microimmunofluorescence (MIF), or complement fixation assays may be used to detect Chlamydia pneumoniae-specific antibodies and assess recent or past infection. Culture is technically demanding because the organism is an obligate intracellular pathogen and is rarely performed outside specialized laboratories. Diagnosis often relies on a combination of clinical presentation, imaging findings, and laboratory testing due to the nonspecific nature of symptoms.
Symptoms Chlamydia pneumoniae infection typically develops following an incubation period of approximately three to four weeks. The disease commonly presents as a mild upper respiratory tract infection characterized by sore throat, hoarseness, runny nose, headache, fatigue, and low-grade fever. Infection may progress to bronchitis or atypical pneumonia, resulting in persistent dry cough, chest discomfort, shortness of breath, and malaise. Symptoms often develop gradually and may persist for several weeks. While most infections are self-limiting, severe disease can occur in elderly individuals, immunocompromised patients, and those with underlying cardiopulmonary disorders. Reinfections are common throughout life due to incomplete protective immunity.

Data

FAQ & Publications

Frequently Asked Questions

What is the primary application of the Chlamydia pneumoniae EB and RB Antigen BA1371VSER?

The antigen is primarily used for the detection of IgA, IgG, and IgM antibodies against Chlamydia pneumoniae in ELISA assays, specifically indirect and quantitative types.

How should the Chlamydia pneumoniae EB and RB Antigen be stored to maintain stability?

The antigen should be stored at -65°C or lower, avoiding repeated freeze-thaw cycles, and should be sonicated before use to preserve its stability and functionality.

Is this antigen suitable for detecting antibodies from species other than Chlamydia pneumoniae?

No, the antigen is specific to Chlamydia pneumoniae and is reactive only to this species.

What form and size does the Chlamydia pneumoniae EB and RB Antigen BA1371VSER come in?

This product is supplied as a liquid form antigen with a lot-specific concentration specified in mg/mL, and is available in a 1 mg size.

What is the recommended shelf life for this antigen under proper storage conditions?

Under the recommended storage conditions of -65°C or lower, the antigen has a shelf life of 10 years from the date of manufacture.

Publications

pmid	title	authors	citation
We haven't added any publications to our database yet.

Published literature highly relevant to the biological target of this product and referencing this antibody or clone are retrieved from the PubMed database provided by the United States National Library of Medicine at the National Institutes of Health.