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MGMT

MGMT (O6-methylguanine-DNA methyltransferase): MGMT is a DNA repair enzyme, and its expression status is crucial in glioblastoma. Loss of MGMT expression can indicate sensitivity to alkylating agents, such as temozolomide, making it a vital biomarker for personalized treatment strategies.



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Human colon carcinoma stained with MGMT antibody using peroxidase-conjugate and DAB chromogen. Note the nuclear staining of tumor cells.
IHC with antibody [6254] : Human colon carcinoma stained with MGMT antibody using peroxidase-conjugate and DAB chromogen. Note the nuclear staining of tumor cells.
Formalin-fixed, paraffin-embedded human glioma stained with MGMT antibody using peroxidase-conjugate and DAB chromogen. Note the nuclear staining of tumor cells
IHC with antibody [6255] : Formalin-fixed, paraffin-embedded human glioma stained with MGMT antibody using peroxidase-conjugate and DAB chromogen. Note the nuclear staining of tumor cells
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