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IgG4
IgG4: IgG4 is an immunoglobulin subtype often associated with IgG4-related disease, which involves autoimmune processes. Its detection through IHC is essential in diagnosing conditions such as IgG4-related sclerosing pancreatitis, aiding in distinguishing these from other inflammatory conditions.
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IHC with antibody [6224] : Human salivary gland stained with anti-IgG4 antibody using peroxidase-conjugate and DAB chromogen. Note the cytoplasmic staining of plasma cells.
IHC with antibody [6225] : Human tonsil stained with anti-IgG4 antibody using peroxidase-conjugate and DAB chromogen. Note the cytoplasmic staining of plasma cells.
