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Granzyme B
Granzyme B: Granzyme B is a serine protease released by cytotoxic T cells and natural killer cells, indicating an immune response against tumors. Its expression in tumor tissues helps assess T-cell infiltration and immune evasion, guiding treatment decisions.
| target | type | reactivity | applications | ||||
|---|---|---|---|---|---|---|---|
| 6203 | Granzyme B | rabbit monoclonal (ZR432) | human | IHC | |||
| 6204 | Granzyme B | mouse monoclonal (ZM66) | human | IHC | |||
IHC with antibody [6203] : Human tonsil stained with anti-Granzyme B antibody using peroxidase-conjugate and DAB chromogen. Note cytoplasmic granular staining of cytotoxic T-cells.
IHC with antibody [6204] : Human tonsil stained with anti-Granzyme B antibody using peroxidase-conjugate and DAB chromogen. Note cytoplasmic granular staining of cytotoxic T-cells.
