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E-cadherin

E-cadherin: E-cadherin is a cell adhesion molecule critical for maintaining epithelial integrity. Its loss of expression is often seen in invasive cancers, especially in breast and gastric tumors. Assessing E-cadherin expression aids in evaluating tumor invasiveness and metastatic potential.



Formalin-fixed paraffin-embedded human breast lobular anti-E-Cadherin antibody using peroxidase-conjugate and DAB chromogen. Note the strong membranous staining of ductal cells (top), whereas tumor cells show weak cytoplasmic staining.
IHC with antibody [6164] : Formalin-fixed paraffin-embedded human breast lobular anti-E-Cadherin antibody using peroxidase-conjugate and DAB chromogen. Note the strong membranous staining of ductal cells (top), whereas tumor cells show weak cytoplasmic staining.
Human infiltrating breast carcinoma stained with anti-E-cadherin antibody using peroxidase-conjugate and DAB chromogen. Note the membrane staining of carcinoma cells.
IHC with antibody [6165] : Human infiltrating breast carcinoma stained with anti-E-cadherin antibody using peroxidase-conjugate and DAB chromogen. Note the membrane staining of carcinoma cells.
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