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DOG-1
DOG-1: DOG-1 is a marker associated with gastrointestinal stromal tumors (GISTs) and is used to confirm diagnosis alongside CD117. Its expression aids in distinguishing GISTs from other mesenchymal tumors, guiding appropriate treatment strategies.
| target | type | reactivity | applications | ||||
|---|---|---|---|---|---|---|---|
| 6160 | DOG-1 | mouse monoclonal (DOG1.1) | human | IHC | |||
| 6161 | DOG-1 | rabbit monoclonal (ZR146) | human | IHC | |||
IHC with antibody [6160] : GIST stained with DOG-1 antibody using peroxidase-conjugate and DAB chromogen. Note the strong cytoplasmic staining of tumor cells.
IHC with antibody [6161] : Formalin-fixed, paraffin-embedded GIST stained with ZR146 antibody using peroxidase-conjugate and DAB chromogen. Note the strong cytoplasmic staining of tumor cells
