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Cytokeratin

Cytokeratin: Cytokeratins are a family of intermediate filament proteins used as markers for epithelial origin in tumors. Specific cytokeratins help differentiate between carcinoma subtypes, allowing pathologists to classify tumors accurately and assess their aggressiveness, making them indispensable in both diagnostic and prognostic assessments.



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Human breast stained with antibody CAM 5.2 using peroxidase-conjugate and DAB chromogen. Note the cytoplasmic staining of ductal cells.
IHC with antibody [6134] : Human breast stained with antibody CAM 5.2 using peroxidase-conjugate and DAB chromogen. Note the cytoplasmic staining of ductal cells.
Human skin with carcinoma stained with anti-HMW, CK antibody using peroxidase-conjugate and DAB chromogen. Note membrane and cytoplasmic staining of squamous epithelium.
IHC with antibody [6154] : Human skin with carcinoma stained with anti-HMW, CK antibody using peroxidase-conjugate and DAB chromogen. Note membrane and cytoplasmic staining of squamous epithelium.
Human liver stained with anti-pan cytokeratin OSCAR antibody using peroxidase-conjugate and DAB chromogen. Note the cytoplasmic staining of ductal cells (strong) and  hepatocytes (weak).
IHC with antibody [6155] : Human liver stained with anti-pan cytokeratin OSCAR antibody using peroxidase-conjugate and DAB chromogen. Note the cytoplasmic staining of ductal cells (strong) and hepatocytes (weak).