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BCL-6
BCL-6: BCL-6 is a transcriptional repressor involved in B-cell maturation and is used as a marker in diagnosing certain lymphomas, particularly diffuse large B-cell lymphoma. Its expression helps identify the germinal center origin of the tumor and can provide prognostic information.
| target | type | reactivity | applications | ||||
|---|---|---|---|---|---|---|---|
| 6031 | BCL-6 | rabbit monoclonal (ZR380) | human | IHC | |||
| 6443 | BCL-6 | mouse monoclonal (ZM22) | human | IHC | |||
IHC with antibody [6443] : Human reactive lymph node stained with anti-BCL-6 antibody using peroxidase-conjugate and DAB chromogen. Note nuclear staining of follicular center B-cells.
IHC with antibody [6031] : Human reactive lymph node stained with anti-BCL-6 antibody using peroxidase-conjugate and DAB chromogen. Note nuclear staining of follicular center B-cells.
