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Bcl-2
Bcl-2: Bcl-2 is an anti-apoptotic protein frequently overexpressed in various malignancies, including follicular lymphoma. Its detection through IHC is critical for understanding the tumor's behavior and potential responses to therapy.
| target | type | reactivity | applications | ||||
|---|---|---|---|---|---|---|---|
| 6028 | BCL-2 | rabbit monoclonal (ZR130) | human | IHC | |||
| 6029 | BCL-2 | mouse monoclonal -124 | human | IHC | |||
IHC with antibody [6028] : Formalin-fixed, paraffin-embedded human tonsil stained with anti-bcl-2 antibody using peroxidase-conjugate and DAB chromogen. Note cytoplasmic and membrane staining of mantle B-cells cells and perifollicular T-cells and no staining of reactive B-cells in the germinal centers
IHC with antibody [6029] : Human reactive lymph node stained with anti-BCL-2 antibody using peroxidase-conjugate and DAB chromogen. Note cytoplasmic and membrane staining of mantle B-cells and perifollicular T-cells, and no staining of reactive B-cells in the germinal centers.
