Alpha Synuclein antibodies

Alpha-synuclein is an important cellular marker, particularly relevant in neurobiology, as it is highly expressed in neurons. It plays a key role in synaptic function and neurotransmitter regulation. The protein is primarily associated with neurodegenerative diseases, most notably Parkinson's disease, where abnormal aggregates of alpha-synuclein form Lewy bodies—a hallmark of the disease. Its involvement extends to other neurodegenerative disorders, such as dementia with Lewy bodies and multiple system atrophy, making alpha-synuclein a crucial marker in studying these conditions.Your website offers alpha-synuclein antibodies primarily for use as a loading control in western blotting (WB), which is ideal for quantifying its expression levels in various models. These antibodies are also suitable for use in immunofluorescence (IF) and immunohistochemistry (IHC) applications, enabling researchers to visualize the localization and distribution of alpha-synuclein within tissue sections or cultured cells.Alpha-synuclein is typically found in the cytoplasm of neurons, and studying its structure can reveal insights into cytoskeletal interactions and potential dysfunction in disease states. By offering high-quality alpha-synuclein antibodies, your website supports research into understanding neurodegenerative processes and advancing the field of neuroscience through WB, IF, and IHC techniques.