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Hello Scientist,
We are reaching out to you by way of introduction due to your publications pertaining to Oxidative Stress and DNA/RNA damage.
Oxidative modifications to nucleic acids—particularly 8-oxoA and 8-hydroxyG—are well-established biomarkers of genotoxic stress, implicated in neurodegeneration, cancer, aging, and inflammatory disease. Precise detection of these lesions is critical for elucidating mechanisms of cellular damage and repair.
Benchmark Antibodies is excited to introduce two new high-affinity Benchmark monoclonal antibodies for oxidative nucleic acid damage detection.
Why These Antibodies Matter:
Oxidized bases like 8-oxoA and 8-OHG serve as early markers of oxidative stress
Enable detection of RNA oxidation, a growing focus in neurobiology and aging research
Support studies in DNA repair mechanisms, carcinogenesis, and mitochondrial dysfunction
Compatible with multiple sample types including tissue sections, cell lysates, and purified nucleic acids
â–º mouse anti-8-hydroxy Guanosine DNA/RNA damage monoclonal antibody (15A3) 1102
Clone 15A3 is a gold-standard antibody cited in dozens of high-impact publications. It detects 8-OHG and 8-oxoG in both DNA and RNA, with applications in immunohistochemistry, ELISA, and dot blot. This lesion is a hallmark of oxidative RNA damage and has been linked to neurodegenerative diseases such as Alzheimer’s, Parkinson’s, and ALS.
â–º mouse anti-8-oxo Adenosine DNA/RNA damage monoclonal antibody (6E4) 1002
8-oxoA is a less commonly studied but biologically significant lesion resulting from oxidative stress. Its presence interferes with normal base pairing and may contribute to mutagenesis and impaired RNA function. Clone 6E4 enables specific and sensitive detection of 8-oxoA in DNA and RNA, supporting advanced mechanistic studies.
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Distribution of 8-oxoG in Arsenite-treated HeLa cells using Mouse anti-8-hydroxy Guanosine DNA/RNA Damage Monoclonal Antibody (Clone 15A3) Catalogue# 1102
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RELIABLE QUALITY
– ISO/GMP monoclonal manufacturing and IVD validation guarantees batch consistency and reproducibility
ECONOMICAL
– IVD workflow reagents ensure uninterrupted supply and lowest market prices
EASY-TO-USE
– Well characterized protocols with real-time North American technical support and order fulfillment
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Mouse anti-8-oxo Adenosine DNA/RNA Damage Monoclonal Antibody (Clone 6E4)
Catalog #1002 exhibiting specificity for all 8-OxoA forms and high selectivity over 8-OxoG.
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Please visit us and feel free to contact us if you have any questions or if we can provide you with additional information.
We look forward to hearing from you!
Best regards,
Team Benchmark
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