SARS-CoV-2 Spike Ectodomain (S1-S2) Antigen BA400R03

$1,752.00

Summary

Virion/Serion Immunologics Antigen for research use (RUO)
SARS-CoV-2 Spike Ectodomain (S1-S2) Antigen, recombinant
Suitable for detection of IgA, IgG & IgM antibodies in ELISA
Lot specific concentration, specified in mg/mL
1 mg

SKU: BA400R03 Category: Infectious disease proteins Tags: antigen, SARS-CoV-2

Weight	1 lbs
Dimensions	9 × 5 × 2 in
target	SARS-CoV-2 Spike Ectodomain (S1-S2)
species reactivity	SARS-CoV-2
applications	ELISA
assay type	Indirect & quantitative
available size	1 mg

SARS-CoV-2 Spike Ectodomain (S1-S2) Antigen BA400R03

kit
Research area Infectious Disease
Storage Store -65°C or below. Avoid repeated freeze-thaw cycles. Avoid repeated freeze-thaw cycles.
Form liquid
Associated products SARS-CoV-2 Spike Ectodomain (S1-S2) Antigen (BA400R03) SARS-CoV-2 Nucleoprotein Antigen (BA400R04) SARS-CoV-2 Human IgA Assay Control (BC400A) SARS-CoV-2 Human IgG Assay Control (BC400G) SARS-CoV-2 Human IgM Assay Control (BC400M) SARS-CoV-2 IgA Agile ELISA Kit (ESR400A) SARS-CoV-2 IgG Agile ELISA Kit (ESR400G) SARS-CoV-2 IgM Agile ELISA Kit (ESR400M)

target relevance
SARS-CoV-2
Description Virus that causes Coronavirus Disease 2019 (COVID-19)
Structure Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is an enveloped, positive-sense, single-stranded RNA virus belonging to the genus Betacoronavirus within the family Coronaviridae. The viral genome is approximately 30 kilobases in length, making it one of the largest known RNA virus genomes. The virus is characterized by prominent spike (S) glycoproteins projecting from the viral envelope, which mediate attachment to host cells through the angiotensin-converting enzyme 2 (ACE2) receptor. SARS-CoV-2 primarily infects epithelial cells of the respiratory tract but can affect multiple organ systems including the cardiovascular, gastrointestinal, neurological, and renal systems. Since its emergence in late 2019, the virus has evolved into numerous variants through genetic mutation and selection, resulting in changes in transmissibility, immune evasion, and disease severity.
Diagnosis The diagnosis of SARS-CoV-2 infection is performed through the detection of viral RNA, viral antigens, or virus-specific antibodies. Reverse transcription polymerase chain reaction (RT-PCR) remains the gold standard for the detection of viral RNA in respiratory specimens and provides high sensitivity and specificity. Rapid antigen tests are widely used for point-of-care diagnosis and screening, although they are generally less sensitive than molecular methods. Serological assays, including ELISA-based tests, may be used to detect antibodies generated following infection or vaccination and are useful for epidemiological studies and assessment of immune responses. Laboratory findings in severe cases may include elevated inflammatory markers, lymphopenia, and abnormalities in coagulation parameters.
Symptoms SARS-CoV-2 is primarily transmitted through respiratory droplets, aerosols, and direct contact with contaminated secretions. Following an incubation period of approximately two to fourteen days, infected individuals may develop fever, cough, fatigue, headache, sore throat, nasal congestion, myalgia, and loss of taste or smell. Additional manifestations may include gastrointestinal symptoms such as nausea, vomiting, and diarrhea. Disease severity ranges from asymptomatic infection to severe pneumonia, acute respiratory distress syndrome (ARDS), multi-organ failure, and death. Elderly individuals and patients with underlying medical conditions are at increased risk of severe disease. Persistent symptoms following acute infection, commonly referred to as post-COVID condition or Long COVID, may affect multiple organ systems and persist for weeks or months after the initial illness.

Data

FAQ & Publications

Frequently Asked Questions

What is the recommended storage condition for the SARS-CoV-2 Spike Ectodomain (S1-S2) Antigen BA400R03?

The SARS-CoV-2 Spike Ectodomain (S1-S2) Antigen BA400R03 should be stored at -65°C or below. It is important to avoid repeated freeze-thaw cycles to maintain antigen integrity.

For which antibody isotypes is the SARS-CoV-2 Spike Ectodomain (S1-S2) Antigen BA400R03 suitable in ELISA applications?

The antigen is suitable for the detection of IgA, IgG, and IgM antibodies in ELISA assays, enabling indirect and quantitative measurement of these antibody classes.

Publications

pmid	title	authors	citation
We haven't added any publications to our database yet.

Published literature highly relevant to the biological target of this product and referencing this antibody or clone are retrieved from the PubMed database provided by the United States National Library of Medicine at the National Institutes of Health.