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PRAME

PRAME: Preferentially expressed antigen in melanoma (PRAME) is a cancer/testis antigen often expressed in various tumors. Its detection can aid in diagnosis and understanding the immune response to tumors.



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Formalin-fixed, paraffin-embedded human liver with metastatic melanoma stained with anti-PRAME antibody using peroxidase-conjugate and DAB chromogen. Note the nuclear staining in tumor cells
IHC with antibody [6345] : Formalin-fixed, paraffin-embedded human liver with metastatic melanoma stained with anti-PRAME antibody using peroxidase-conjugate and DAB chromogen. Note the nuclear staining in tumor cells