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CD117

CD117 (c-KIT): CD117 is a receptor tyrosine kinase marker essential for diagnosing gastrointestinal stromal tumors (GISTs). Its detection through IHC confirms GIST diagnosis, guiding treatment with imatinib, a targeted therapy that specifically inhibits CD117.



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Human GIST stained with anti-CD117 antibody using peroxidase-conjugate and DAB chromogen. Note cell membrane staining of tumor cells.
IHC with antibody [6055] : Human GIST stained with anti-CD117 antibody using peroxidase-conjugate and DAB chromogen. Note cell membrane staining of tumor cells.
Formalin-fixed, paraffin-embedded human GIST stained with anti-CD117 antibody using peroxidase-conjugate and DAB chromogen. Note cell membrane staining of tumor cells
IHC with antibody [6056] : Formalin-fixed, paraffin-embedded human GIST stained with anti-CD117 antibody using peroxidase-conjugate and DAB chromogen. Note cell membrane staining of tumor cells
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