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BRG1/SMARC4

BRG1/SMARC4: BRG1 is a key component of the SWI/SNF chromatin remodeling complex and is relevant in various malignancies. Its loss of expression is associated with aggressive tumor behavior, making it a valuable marker for prognosis.



Formalin-fixed and paraffin-embedded human ovarian small cell carcinoma stained with anti-ERG1 antibody using peroxidase-conjugate and DAB chromogen. Note the absence of nuclear staining of tumor cells were retained nuclear staining of background inflammatory cells and endothelial cells
IHC with antibody [6039] : Formalin-fixed and paraffin-embedded human ovarian small cell carcinoma stained with anti-ERG1 antibody using peroxidase-conjugate and DAB chromogen. Note the absence of nuclear staining of tumor cells were retained nuclear staining of background inflammatory cells and endothelial cells