Actin Muscle Specific Msa

Actin Muscle Specific Msa

: Muscle Specific Actin (MSA) is a pan-muscle marker, recognizing alpha and gamma actin isomers essential for muscle cell contraction and structural integrity. Its presence is the gold standard for recognizing neoplasms of muscle differentiation, setting it apart from other mesenchymal tumors. Aberrant expression or modification of Actin Muscle Specific Msa is often implicated in the pathology of key diseases, making it a crucial biomarker and a prime focus for translational research and drug development.

The diagnostic utility of Immunohistochemistry (IHC) for Actin Muscle Specific Msa is unparalleled in its specific application. In surgical pathology, IHC with MSA (HHF35 clone) is crucial for diagnosing soft tissue tumors like leiomyoma, leiomyosarcoma, and rhabdomyosarcoma. Its robust positive staining confirms a muscle lineage, providing a key step in the diagnostic pathway for these often aggressive malignancies. Accurate analysis of expression and localization using highly specific monoclonal antibodies allows researchers and pathologists to achieve superior diagnostic resolution and drive better patient stratification.