Herpes simplex Virus 1 and 2 IgG Lateral flow dipstick kit 5372

Herpes simplex Virus 1 and 2 IgG Lateral flow dipstick kit 5372 - Image 2

Herpes simplex Virus 1 and 2 IgG Lateral flow dipstick kit 5372

$478.00

Summary

Mikrogen diagnostik lateral flow device (dipstick) for research use (RUO)
Herpes Simplex Virus (HSV) 1 and 2 IgG ELISA Kit
Suitable for IgG detection
Ready-to-use
20 tests

SKU: 5372 Category: kits Tags: Herpes simplex Virus, IgG, Lateral Flow Dipsticks

Weight	1 lbs
Dimensions	9 × 5 × 2 in
target	Herpes simplex Virus 1 and 2 reactive IgG
species reactivity	Herpes Simplex Virus
applications	Lateral flow (dipstick)
assay type	Indirect & qualitative
available sizes	2x 20 test kits

Herpes simplex Virus 1 and 2 IgG Lateral flow dipstick 5372

Assay type
Sandwich assay, lateral flow (dipstick)

Research area
Infectious Disease

Sample type
Serum, plasma, whole blood

Components

10X Wash Buffer	100 mL
TMB Substrate	40 mL
Milk Powder	5 g
Instructions for Use	1 Each
Evaluation Form	1 Each
Test Strips	2 kits of [2 Vials x 10 Each]
Anti-Human IgG Conjugate	500 ?L
Positive Control	140 ?L
Negative Control	140 ?L

Storage
Store at 2-8°C.

Additional information
Mikrogen recomLine HSV-1 & HSV-2 IgG Test

Mikrogen recomLine HSV-1 & HSV-2 IgG Test is a serological, qualitative in vitro line immunoassay based on purified, subtype-specific recombinant gG1 (HSV-1) and gG2 (HSV-2) antigens, ensuring accurate differentiation of HSV-1 and HSV-2 infections.

Most serologic methods for determining HSV status use viral lysate as antigens and cannot distinguish between HSV-1 and HSV-2 infections due to cross-reactivity. Since most adults have already had an HSV-1 infection (seroprevalence is approximately 83% in Germany), serological status for HSV-2 cannot be reliably diagnosed using viral lysates.

Advantages

Highest sensitivity and specificity due to the use of recombinant antigens: gG1 (HSV-1) and gG2 (HSV-2).
Application as serological confirmation or supplement for PCR and/or cell culture findings, after positive screening with HSV ELISA.
Application for determination of subtype-specific HSV serostatus of risk groups:
- Herpes genitalis positive patients and their partners.
- Patients with an increased risk for sexually transmitted diseases.
- Immunosuppressed patients (e.g., HIV seropositive, transplant patients).
- Recurrent genital and anal infections.
- Pregnancy (risk assessment of primary HSV infection or risk of herpes neonatorum).
No cross-reactions.
Easy and clear interpretation due to easy-to-read banding.
Partial and full automation, software-based evaluation (recomScan), and integration with laboratory information system possible.

target relevance
Organism Herpes Simplex Virus 1/2
Structure and strains Herpes simplex virus 1 and 2 (HSV-1 and HSV-2), also known by their taxonomic names Human alphaherpesvirus 1 and Human alphaherpesvirus 2, are two members of the human Herpesviridae family, a set of viruses that produce viral infections in the majority of humans. Both HSV-1 and HSV-2 are very common and contagious. They can be spread when an infected person begins shedding the virus. As of 2016, about 67% of the world population under the age of 50 had HSV-1. In the United States, about 47.8% and 11.9% are estimated to have HSV-1 and HSV-2, respectively, though actual prevalence may be much higher. Because it can be transmitted through any intimate contact, it is one of the most common sexually transmitted infections.
Disease Herpes Simplex Virus 1 (HSV 1) and Herpes Simplex Virus 2 (HSV 2) are DNA viruses belonging to the family of Herpesviridae. They occur globally. In industrialized countries the seroprevalence amounts to 50% in the second decade of life, in adults even up to 90% for HSV 1 and 10 to 15% for HSV 2. The transmission of Herpes Simplex Virus 1 occurs by contact with contaminated salivary or smear infection. Herpes Simplex Virus 2 is transmitted via contact with infected mucosal skin. Primary HSV 1 infections process inapparently in 90% of cases. 10% of infected persons suffer from inflammations of cornea and conjunctiva or show the characteristic herpes vesiculation at the lips. These pustular eruptions can spread on eczematous skin with life-threatening effects. Other complications are encephalitis or meningoencephalitis. 12% of primary HSV 2 infections are apparent with sudden abortion, vulvovaginitis or penis scrotum efflorescences.
Detection and diagnosis An important field of application for HSV serology - also during latency - is the detection of serotype-specific HSV IgG antibodies in order to identify potential HSV carriers who could infect susceptible individuals. In particular, the identification of HSV 2 serotype-specific antibodies in pregnant women, who present a high risk of transferring the virus to a newborn child, is recommended. The serological typing of an HSV infection is usually performed by identifying IgG antibodies directed against the viral surface glycoproteins G (gG) of HSV 1 (gG1) and HSV 2 (gG2). Due to the fact that these antibodies are only produced some weeks after a primary infection, the determination of serotype-specific antibodies can also assist in the differentiation between primary infection and reactivation

Data

Publications

pmid	title	authors	citation
We haven't added any publications to our database yet.

Published literature highly relevant to the biological target of this product and referencing this antibody or clone are retrieved from PubMed database provided by The United States National Library of Medicine at the National Institutes of Health.