Affinity of proteins A and G for IgG from various species
| Animal | IgG Affinity for Protein A | IgG Affinity for Protein G |
|---|---|---|
| Human | High | High |
| Mouse | Low | High |
| Rat | Low | High |
| Rabbit | Low | High |
| Goat | Low | High |
| Sheep | Low | High |
| Guinea | Low | High |
| Cow | Low | High |
| Horse | Low | High |
| Chicken | Low | Low |
| Pig | Low | Moderate |
| Dog | Low | Moderate |
| Cat | Low | Moderate |
Affinity of proteins A and G for human Immunoglobulins
| Immunoglobulin | Affinity for Protein A | Affinity for Protein G |
|---|---|---|
| IgA | Low | Low |
| IgD | Low | Low |
| IgE | Low | Low |
| IgG1 | Moderate to High | Moderate to High |
| IgG2 | Low | High |
| IgG3 | Low to Moderate | Low to Moderate |
| IgG4 | Low | Moderate |
| IgM | Low | Low to Moderate |