Afp
: Alpha-fetoprotein (AFP) is a classic oncofetal antigen, normally produced by the fetal liver and yolk sac. Its re-expression in adults signals malignant transformation, establishing AFP as a primary serum and tissue-based tumor marker. Aberrant expression or modification of Afp is often implicated in the pathology of key diseases, making it a crucial biomarker and a prime focus for translational research and drug development.
The diagnostic utility of Immunohistochemistry (IHC) for Afp is unparalleled in its specific application. As a diagnostic IHC marker, AFP is highly specific for confirming the diagnosis of Hepatocellular Carcinoma (HCC) and Yolk Sac Tumors. Visualizing AFP expression in tumor cells provides crucial diagnostic confirmation, helps determine the extent of disease, and is often used as a prognostic indicator that correlates with progression and therapeutic response. Accurate analysis of expression and localization using highly specific monoclonal antibodies allows researchers and pathologists to achieve superior diagnostic resolution and drive better patient stratification.
For research demanding diagnostic-grade precision, selecting a highly validated monoclonal antibody for Afp is non-negotiable. We offer these antibodies, ensuring the specificity and consistency required for both fundamental studies and clinically-relevant research. Explore our highly validated products and their detailed data sheets here: Afp Antibody Product 6014.