Adenovirus

Adenovirus

: Adenoviruses are non-enveloped DNA viruses capable of causing a wide range of infections, from respiratory illness to tissue-invasive disease, which can be life-threatening, particularly in immunocompromised patients. Aberrant expression or modification of Adenovirus is often implicated in the pathology of key diseases, making it a crucial biomarker and a prime focus for translational research and drug development.

The diagnostic utility of Immunohistochemistry (IHC) for Adenovirus is unparalleled in its specific application. The diagnostic utility of Adenovirus IHC lies in its ability to detect viral antigens directly within formalin-fixed, paraffin-embedded tissue. This method is often indispensable for confirming tissue-invasive adenoviral disease in sites like the lung or liver, where standard culture or antigen detection methods may lack sufficient sensitivity in compromised hosts. Accurate analysis of expression and localization using highly specific monoclonal antibodies allows researchers and pathologists to achieve superior diagnostic resolution and drive better patient stratification.