| Weight | 1 lbs |
|---|---|
| Dimensions | 9 × 5 × 2 in |
| concentration | 1 mg/mL |
| applications | IP, WB |
| reactivity | MDA-BSA, protein |
| available sizes | 0.5 mg |
MDA modified BSA protein 1006
$400.00
Antibody summary
- Rabbit polyclonal to Malondialdehyde (MDA)
- Suitable for: WB,IP
- Reacts with: MDA modified protein
- Isotype:
- 0.5 mg
mda anti-gen 1006
| antibody |
|---|
| Tested applications WB,IP |
| Size and concentration 500µg and 1 mg/mL |
| Form liquid |
| Storage Instructions Store at -20°C |
| Storage buffer 10 mM PBS, 0.15 M NaCl, 0.5 mM EDTA, 0.01% NaN3, 50% glycerol |
| target relevance |
|---|
| MDA |
| Protein names Malondialdehyde |
| Alternative names MDA, Malonic dialdehyde, Propanedial |
| Function MDA is a reactive end-product of lipid peroxidation and can form covalent adducts with proteins, lipids, and nucleic acids. |
| Post-translational modification MDA reacts with lysine, histidine, arginine, and other nucleophilic residues to form stable MDA-protein adducts. These modified molecules are often immunogenic and are recognized by anti-MDA antibodies. |
| Involvement in disease Elevated MDA levels have been associated with cardiovascular disease, atherosclerosis, diabetes, neurodegenerative disorders, chronic inflammation, cancer, and aging. |
| Description Malondialdehyde (MDA) is a highly reactive aldehyde generated during lipid peroxidation of polyunsaturated fatty acids. It is one of the most widely used biomarkers of oxidative stress and lipid oxidation. |
| Chemical description Reactive aldehyde C3H4O2 72.06 Da |
| Related entities relationship: forms_adduct_with; entity: Low-density lipoprotein relationship: forms_adduct_with; entity: Albumin relationship: forms_adduct_with; entity: Proteins relationship: derived_from; entity: Lipid peroxidation relationship: related_to; entity: 4-Hydroxynonenal relationship: related_to; entity: Oxidized LDL relationship: related_to; entity: MDA-LDL |
| Keywords Reactive aldehyde, Lipid peroxidation, Oxidative stress, Oxidative damage, Biomarker |
| Structure Malondialdehyde is a small reactive dialdehyde (propanedial) generated during oxidative degradation of polyunsaturated lipids. |
| Formation MDA is produced as a terminal product of lipid peroxidation during oxidative stress and inflammatory processes. |
| Protein modification MDA readily reacts with amino groups on proteins to form MDA-protein adducts, which can alter protein function and generate neoepitopes recognized by the immune system. |
| Clinical relevance Elevated MDA concentrations are associated with oxidative stress, cardiovascular disease, diabetes, neurodegeneration, chronic inflammation, and cancer. |
| Research relevance MDA is widely used as a biomarker of lipid peroxidation and oxidative damage and is frequently measured by ELISA, TBARS assays, HPLC, and mass spectrometry. |
Data
| No results found |
FAQ & Publications
Frequently Asked Questions
What is the recommended storage condition for the MDA modified BSA protein 1006?
The MDA modified BSA protein 1006 should be stored at -20°C to maintain stability and activity.
Which applications is the Rabbit polyclonal antibody to Malondialdehyde (MDA) suitable for?
This antibody is suitable for Western blot (WB) and immunoprecipitation (IP) applications.
What is the concentration and form of the MDA modified BSA protein 1006 provided?
The protein is supplied as a liquid at a concentration of 1 mg/mL.
Does the MDA antibody react specifically with any proteins?
Yes, it reacts specifically with MDA modified proteins, such as MDA-BSA.
Publications
| pmid | title | authors | citation |
|---|---|---|---|
| We haven't added any publications to our database yet. | |||
Published literature highly relevant to the biological target of this product and referencing this antibody or clone are retrieved from the PubMed database provided by the United States National Library of Medicine at the National Institutes of Health.
Protocols
| relevant to this product |
|---|
| Western blot |
Documents
| Batch Number | QC File | SDS |
|---|---|---|
| To view batch-specific Safety Datasheets and Quality Certificates associated with your account, please Log In. | ||
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