ELISA with Biotinylated Cynomolgus ACE2/ACEH Protein 4682

Biotinylated Cynomolgus ACE2/ACEH Protein 4682

$525.00 – $1,750.00

Summary

Expression: HEK293
Functional: Yes (ELISA)
Amino Acid Range: Gln18-Val739

SKU: 4682parent Categories: proteins, Recombinant proteins Tag: active proteins

Weight	1 lbs
Dimensions	9 × 5 × 2 in
express system	HEK293
product tag	C-His-Avi
purity	> 95% as determined by Tris-Bis PAGE;> 95% as determined by HPLC
background	ACE2 (Angiotensin I Converting Enzyme 2) is a Protein Coding gene. Diseases associated with ACE2 include Severe Acute Respiratory Syndrome and Neurogenic Hypertension.The protein encoded by this gene belongs to the angiotensin-converting enzyme family of dipeptidyl carboxydipeptidases and has considerable homology to human angiotensin 1 converting enzyme. This secreted protein catalyzes the cleavage of angiotensin I into angiotensin 1-9, and angiotensin II into the vasodilator angiotensin 1-7.
molecular weight	The protein has a predicted MW of 86.5 kDa. Due to glycosylation, the protein migrates to 110-140 kDa based on Tris-Bis PAGE result.
available size	100 µg, 500 µg
endotoxin	Less than 1EU per μg by the LAL method.

Biotinylated Cynomolgus ACE2/ACEH Protein 4682

protein

Size and concentration 100, 500µg and lyophilized
Form Lyophilized
Storage Instructions Valid for 12 months from date of receipt when stored at -80°C. Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
Storage buffer Shipped at ambient temperature.
Purity > 95% as determined by Tris-Bis PAGE

target relevance
ACE2 (Angiotensin I Converting Enzyme 2) is a Protein Coding gene. Diseases associated with ACE2 include Severe Acute Respiratory Syndrome and Neurogenic Hypertension.The protein encoded by this gene belongs to the angiotensin-converting enzyme family of dipeptidyl carboxydipeptidases and has considerable homology to human angiotensin 1 converting enzyme. This secreted protein catalyzes the cleavage of angiotensin I into angiotensin 1-9, and angiotensin II into the vasodilator angiotensin 1-7.
Protein names Angiotensin-converting enzyme (EC 3.4.-.-)
Gene names ACE2,ACE2
Protein family Peptidase M2 family
Mass 9541Da
Subellular location Apical cell membrane. Cell membrane ; Single-pass type I membrane protein. Cell projection, cilium. Cytoplasm. Membrane ; Single-pass type I membrane protein. Secreted .
Target Relevance information above includes information from UniProt accession: A0A2K5X283
The UniProt Consortium

Data

ELISA with Biotinylated Cynomolgus ACE2/ACEH Protein

Immobilized SARS-COV-2 Spike RBD, hFc Tag at 1µg/ml (100µl/Well) on the plate. Dose response curve for Biotinylated Cynomolgus ACE2, His Tag with the EC50 of 0.28µg/ml determined by ELISA.

HPLC of Biotinylated Cynomolgus ACE2/ACEH Protein

The purity of Biotinylated Cynomolgus ACE2 is greater than 95% as determined by SEC-HPLC.

SDS-PAGE gel of Biotinylated Cynomolgus ACE2/ACEH Protein

Biotinylated Cynomolgus ACE2 on Tris-Bis PAGE under reduced condition. The purity is greater than 95%.

Publications

Published literature highly relevant to the biological target of this product and referencing this antibody or clone are retrieved from PubMed database provided by The United States National Library of Medicine at the National Institutes of Health.