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SARS-CoV-2 Spike RBD (Omicron BA.2.75.2) Protein 2633

$345.00$1,150.00

Summary

  • Expression: HEK293
  • Functional: Yes (ELISA)
  • Amino Acid Range: Arg319-Phe541(G339H, R346T, S371F, S373P, S375F, T376A, D405N, R408S, K417N, N440K, G446S, N460K, S477N, T478K, E484A, F486S, Q498R, N501Y, Y505H)
SKU: 2633parent Categories: , Tag:
Weight1 lbs
Dimensions9 × 5 × 2 in
accession

QHD43416

express system

HEK293

product tag

C-His

purity

> 95% as determined by Tris-Bis PAGE;> 95% as determined by HPLC

background

The ongoing coronavirus disease 2019 (COVID-19) pandemic has prioritized the development of small-animal models for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). The resulting mouse-adapted strain at passage 6 (called MASCp6) showed increased infectivity in mouse lung and led to interstitial pneumonia and inflammatory responses in both young and aged mice after intranasal inoculation. Deep sequencing revealed a panel of adaptive mutations potentially associated with the increased virulence. In particular, the N501Y mutation is located at the receptor binding domain (RBD) of the spike protein.

molecular weight

The protein has a predicted MW of 26.28 kDa. Due to glycosylation, the protein migrates to 35-43 kDa based on Tris-Bis PAGE result.

available size

100 µg, 500 µg

endotoxin

Less than 1EU per μg by the LAL method.

SARS-CoV-2 Spike RBD (Omicron BA.2.75.2) Protein 2633

protein
Size and concentration
100, 500µg and lyophilized
Form
Lyophilized
Storage Instructions
Valid for 12 months from date of receipt when stored at -80°C. Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
Storage buffer
Shipped at ambient temperature.
Purity
> 95% as determined by Tris-Bis PAGE
No information
target relevance

ELISA with SARS-CoV-2 Spike RBD (Omicron BA.2.75.2) Protein
Immobilized SARS-CoV-2 Spike RBD (Omicron BA.2.75.2), His Tag at 0.5µg/ml (100µl/Well) on the plate. Dose response curve for Human ACE2, hFc Tag with the EC50 of 8.9ng/ml determined by ELISA.
HPLC of SARS-CoV-2 Spike RBD (Omicron BA.2.75.2) Protein
The purity of SARS-CoV-2 Spike RBD (Omicron BA.2.75.2) is greater than 95% as determined by SEC-HPLC.
SDS-PAGE gel of SARS-CoV-2 Spike RBD (Omicron BA.2.75.2) Protein
SARS-CoV-2 Spike RBD (Omicron BA.2.75.2) on Tris-Bis PAGE under reduced condition. The purity is greater than 95%.

Publications

pmidtitleauthorscitation
We haven't added any publications to our database yet.
Published literature highly relevant to the biological target of this product and referencing this antibody or clone are retrieved from PubMed database provided by The United States National Library of Medicine at the National Institutes of Health.

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