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RSV (B) Post-fusion glycoprotein F0 Protein 2221

$675.00$2,250.00

Summary

  • Expression: HEK293
  • Functional: Yes (ELISA)
  • Amino Acid Range:
SKU: 2221parent Categories: , Tag:
Weight1 lbs
Dimensions9 × 5 × 2 in
accession
express system

HEK293

product tag

C-His

purity

> 95% as determined by Tris-Bis PAGE

background

Respiratory syncytial virus (RSV) is a highly contagious childhood pathogen of the respiratory tract and is divided into two antigenic subtypes, A and B, based on the reactivity of the F and G surface proteins to monoclonal antibodies. Surface protein F (fusion protein) is responsible for fusion of viral and host cell membranes, as well as syncytium formation between viral particles. Its sequence is highly conserved between strains. F protein exists in multiple conformational forms. In the prefusion state (PreF), the protein exists in a trimeric form and contains the major antigenic site Ø which serves as a primary target of neutralizing antibodies in the body.

molecular weight

The protein has a predicted MW of 55.96 kDa. The protein migrates to 18-25 kDa and 42-50 kDa based on Tris-Bis PAGE result.

available size

100 µg, 500 µg

endotoxin

Less than 1EU per μg by the LAL method.

RSV (B) Post-fusion glycoprotein F0 Protein 2221

protein
Size and concentration
100, 500µg and lyophilized
Form
Lyophilized
Storage Instructions
Valid for 12 months from date of receipt when stored at -80°C. Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
Storage buffer
Shipped at ambient temperature.
Purity
> 95% as determined by Tris-Bis PAGE
No information
target relevance

ELISA with RSV (B) Post-fusion glycoprotein F0 Protein
Immobilized RSV (B) Post-fusion glycoprotein F0, His Tag at 1µg/ml (100µl/Well) on the plate. Dose response curve for Anti-Fusion glycoprotein F0 (101F) Antibody, hFc Tag with the EC50 of 3.4ng/ml and not bind Anti-Fusion glycoprotein F0 (D25) Antibody determined by ELISA.
SDS-PAGE gel of RSV (B) Post-fusion glycoprotein F0 Protein
RSV (B) Post-fusion glycoprotein F0 on Tris-Bis PAGE under reduced condition. The purity is greater than 95%.

Publications

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We haven't added any publications to our database yet.
Published literature highly relevant to the biological target of this product and referencing this antibody or clone are retrieved from PubMed database provided by The United States National Library of Medicine at the National Institutes of Health.

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