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Rhesus macaque IL-18 R1/CD218a Protein 2305

$270.00$900.00

Summary

  • Expression: HEK293
  • Functional: Yes (ELISA)
  • Amino Acid Range: Cys22-Gly329
SKU: 2305parent Categories: , Tags: , , ,
Weight1 lbs
Dimensions9 × 5 × 2 in
accession

F7H8F9

express system

HEK293

product tag

C-hFc

purity

> 95% as determined by Tris-Bis PAGE;> 95% as determined by HPLC

background

Interleukin-18 (IL-18) is a member of the interleukin-1 family of cytokines produced constitutively by different cell types and by adipose tissue. Interleukin (IL)-18 was originally discovered as a factor that enhanced IFN-γ production from anti-CD3-stimulated Th1 cells, especially in the presence of IL-12. Upon stimulation with Ag plus IL-12, naïve T cells develop into IL-18 receptor (IL-18R) expressing Th1 cells, which increase IFN-γ production in response to IL-18 stimulation.

molecular weight

The protein has a predicted MW of 61.96 kDa. Due to glycosylation, the protein migrates to 75-95 kDa based on Tris-Bis PAGE result.

available size

100 µg, 500 µg

endotoxin

Less than 1EU per μg by the LAL method.

Rhesus macaque IL-18 R1/CD218a Protein 2305

Data

ELISA with Rhesus macaque IL-18 R1/CD218a Protein
Immobilized Rhesus macaque IL-18 R1, hFc Tag at 1µg/ml (100µl/Well) on the plate. Dose response curve for Biotinylated Human IL-18, No Tag with the EC50 of 0.42µg/ml determined by ELISA.
HPLC of Rhesus macaque IL-18 R1/CD218a Protein
The purity of Rhesus macaque IL-18 R1 is greater than 95% as determined by SEC-HPLC.
SDS-PAGE gel of Rhesus macaque IL-18 R1/CD218a Protein
Rhesus macaque IL-18 R1 on Tris-Bis PAGE under reduced condition. The purity is greater than 95%.

Publications

Published literature highly relevant to the biological target of this product and referencing this antibody or clone are retrieved from PubMed database provided by The United States National Library of Medicine at the National Institutes of Health.




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