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Rhesus macaque EGFR/HER1 Protein 3335

$225.00$750.00

Summary

  • Expression: HEK293
  • Functional: Yes (ELISA)
  • Amino Acid Range: Leu25-Ser645
SKU: 3335parent Categories: , Tags: , , ,
Weight1 lbs
Dimensions9 × 5 × 2 in
accession

P55245

express system

HEK293

product tag

C-His

purity

> 95% as determined by Tris-Bis PAGE;> 95% as determined by HPLC

background

The epidermal growth factor receptor is a transmembrane protein that is a receptor for members of the epidermal growth factor family of extracellular protein ligands. The epidermal growth factor receptor is a member of the ErbB family of receptors, a subfamily of four closely related receptor tyrosine kinases: EGFR, HER2/neu, Her 3 and Her 4. Receptor tyrosine kinase binding ligands of the EGF family and activating several signaling cascades to convert extracellular cues into appropriate cellular responses.

molecular weight

The protein has a predicted MW of 69.8 kDa. Due to glycosylation, the protein migrates to 85-100 kDa based on Tris-Bis PAGE result.

available size

100 µg, 500 µg

endotoxin

Less than 1EU per μg by the LAL method.

Rhesus macaque EGFR/HER1 Protein 3335

Data

ELISA with Rhesus macaque EGFR/HER1 Protein
Immobilized Rhesus macaque EGFR, His Tag at 5µg/ml (100µl/Well) on the plate. Dose response curve for Human EGF, hFc Tag with the EC50 of 5.9ng/ml determined by ELISA.
HPLC of Rhesus macaque EGFR/HER1 Protein
The purity of Rhesus macaque EGFR is greater than 95% as determined by SEC-HPLC.
SDS-PAGE gel of Rhesus macaque EGFR/HER1 Protein
Rhesus macaque EGFR on Tris-Bis PAGE under reduced condition. The purity is greater than 95%.

Publications

Published literature highly relevant to the biological target of this product and referencing this antibody or clone are retrieved from PubMed database provided by The United States National Library of Medicine at the National Institutes of Health.




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