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Rhesus macaque CDH17/Cadherin 17 Protein 2704

$315.00$1,050.00

Summary

  • Expression: HEK293
  • Functional: Yes (ELISA)
  • Amino Acid Range: Gln23-Thr784
SKU: 2704parent Categories: , Tag:
Weight1 lbs
Dimensions9 × 5 × 2 in
accession

A0A1D5R2B4

express system

HEK293

product tag

C-His

purity

> 95% as determined by Tris-Bis PAGE;> 95% as determined by HPLC

background

Liver-intestine cadherin (CDH17) has been known to function as a tumor stimulator and diagnostic marker for almost two decades.In vivo studies showed CDH17 knockout resulted in apoptotic PC tumor death through activating caspase-3 activity. Taken together, CDH17 functions as an oncogenic molecule critical to PC growth by regulating tumor apoptosis signaling pathways and CDH17 could be targeted to develop an anti-PC therapeutic approach.

molecular weight

The protein has a predicted MW of 85.60 kDa. Due to glycosylation, the protein migrates to 90-110 kDa based on Tris-Bis PAGE result.

available size

100 µg, 500 µg

endotoxin

Less than 1EU per μg by the LAL method.

Rhesus macaque CDH17/Cadherin 17 Protein 2704

protein
Size and concentration
100, 500µg and lyophilized
Form
Lyophilized
Storage Instructions
Valid for 12 months from date of receipt when stored at -80°C. Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
Storage buffer
Shipped at ambient temperature.
Purity
> 95% as determined by Tris-Bis PAGE
target relevance
Liver-intestine cadherin (CDH17) has been known to function as a tumor stimulator and diagnostic marker for almost two decades.In vivo studies showed CDH17 knockout resulted in apoptotic PC tumor death through activating caspase-3 activity. Taken together, CDH17 functions as an oncogenic molecule critical to PC growth by regulating tumor apoptosis signaling pathways and CDH17 could be targeted to develop an anti-PC therapeutic approach.
Protein names
Cadherin 17
Gene names
CDH17,CDH17
Mass
9544Da
Target Relevance information above includes information from UniProt accession: A0A1D5R2B4
The UniProt Consortium

ELISA with Rhesus macaque CDH17/Cadherin 17 Protein
Immobilized Rhesus macaque CDH17, His Tag at 0.5µg/ml (100µl/Well) on the plate. Dose response curve for Anti-CDH17 Antibody, hFc Tag with the EC50 of 4.2ng/ml determined by ELISA.
HPLC of Rhesus macaque CDH17/Cadherin 17 Protein
The purity of Rhesus macaque CDH17 is greater than 95% as determined by SEC-HPLC.
SDS-PAGE gel of Rhesus macaque CDH17/Cadherin 17 Protein
Rhesus macaque CDH17 on Tris-Bis PAGE under reduced condition. The purity is greater than 95%.

Publications

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We haven't added any publications to our database yet.
Published literature highly relevant to the biological target of this product and referencing this antibody or clone are retrieved from PubMed database provided by The United States National Library of Medicine at the National Institutes of Health.

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